113723-87-8

Basic information

• Product Name: tert-butyl (R)-3'-phenyl-2'-([1R,2E,4R]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylideneamino)propanoate
• Synonyms: tert-butyl (R)-3'-phenyl-2'-([1R,2E,4R]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylideneamino)propanoate
• CAS NO: 113723-87-8
• Molecular Weight: 355.521
• Mol File: 113723-87-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl (R)-3'-phenyl-2'-([1R,2E,4R]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylideneamino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (R)-3'-phenyl-2'-([1R,2E,4R]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylideneamino)propanoate(113723-87-8)
• EPA Substance Registry System: tert-butyl (R)-3'-phenyl-2'-([1R,2E,4R]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylideneamino)propanoate(113723-87-8)

Safety Data

• Hazardous Substances Data: 113723-87-8(Hazardous Substances Data)

Upstream product

• 53402-10-1 thiocamphor 
• 6456-74-2 Glycine tert-butyl ester 
• 2792-42-9 (R,R)-camphor oxime 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 
• 287488-25-9 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-imine 
• 3403-25-6 tert-butyl (2R)-2-amino-3-phenyl-propanoate hydrochloride 
• 100-39-0 benzyl bromide 
• 104505-09-1 [1,7,7-Trimethyl-bicyclo[2.2.1]hept-(2E)-ylideneamino]-acetic acid tert-butyl ester 
• 104505-09-1 tert-butyl ([1R,2E,4R]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylideneamino)acetate 

Downstream Products

• 104505-14-8 (R)-3-Phenyl-2-[(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylideneamino]-propan-1-ol 
• 3081-28-5 D-phenylalanine tert-butyl ester 
• 104505-15-9 (R)-1-Phenyl-2-[(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylideneamino]-heptan-3-one 
• 104505-16-0 5-{(R)-2-Phenyl-1-[(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylideneamino]-ethyl}-nonan-5-ol 

Relevant articles and documents

Studies on the preparation of camphorylidene derivatives of α-amino acids

An improved method has been developed for the efficient synthesis of stable camphor imine salts. Camphor imine readily undergoes transimination with α-amino acid ester hydrochlorides to yield camphorylidene amino acid derivatives with E stereochemistry about the C=N double bond. Sodium cyanoborohydride reduction of the derived ketimines gives exo-bornylamines.

Diastereoselective Alkylation Guided by Electrophile-Nucleophile ?-Interactions

Alkylation of the enolate 1a obtained from the (R)-camphor imine of tert-butyl glycinate with a variety of alkylating agents gives products whose trends in diastereomeric excesses appear to correlate with ? electron density and steric effects in the elect