113775-57-8Relevant articles and documents
Application of meso-hydrobenzoin-derived chiral auxiliaries for the stereoselective synthesis of highly substituted pyrrolidines by 1,3-dipolar cycloaddition of azomethine ylides
Bica, Katharina,Gaertner, Peter
experimental part, p. 641 - 646 (2010/08/03)
The metal-catalyzed stereoselective 1,3-dipolar cycloaddition of azomethine ylides and acrylates using recyclable meso-hydrobenzoin-derived chiral auxiliaries is described. Cleavage of the auxiliary leads to highly substituted pyrrolidines in up to 87% en
A Separation Procedure for the Preparation of Enantiomerically Pure Midodrine
Noe,Knollmüller,G?rtner
, p. 159 - 165 (2007/10/03)
Racemic midodrine chlorohydrate (rac-1) was N-protected to yield the racemic products rac-2a-c. These were converted into the diastereomeric O-acetals 3a-c/4a-c, which can easily be separated by chromatography. After removal of the N- and O-protective gro
Chiral Lactols, VIII - A Way for the Asymmetric Induction in the Formation of Sugars
Noe, Christian R.,Knollmueller, Max,Ettmayer, Peter
, p. 637 - 644 (2007/10/02)
The substituted glycol aldehyde 4 which bears an enantiomerically pure acetal-type protective group exhibiting the configuration of an α-L-sugar at the acetal centre is subjected to aldolization under basic conditions.The resulting products are reduced and characterized by comparison with reference compounds of known absolute configuration.L-Sugars are formed preferentially with L-erythrose being the main product.