113826-06-5 Usage
Description
(2R)-(-)-Glycidyl tosylate is a white crystalline powder that serves as a protected glycidol and is widely utilized as an intermediate in the synthesis of various compounds, particularly in the field of neurochemistry.
Uses
Used in Pharmaceutical Industry:
(2R)-(-)-Glycidyl tosylate is used as an intermediate for the preparation of neurochemicals, which are essential for understanding and treating neurological disorders and conditions.
Used in Chemical Synthesis:
(2R)-(-)-Glycidyl tosylate is used as a starting material in the synthesis of various compounds, such as:
1. 1-O-hexadecyl-sn-glycerol 3-O-p-toluenesulfonate, which is prepared by reacting with 1-hexadecanol in the presence of boron trifluoride etherate.
2. 4-Oxiranylmethoxy-(1H)-indole, which is synthesized by reacting with 4-hydroxyindole in the presence of sodium hydride.
3. [18F]Epifluorohydin, an intermediate for preparing [18F]fluoromisonidazole, a radiotracer used in medical imaging.
4. 1,2-diacyl-sn-3-glycerophosphocholines, which are important components of cell membranes and have potential applications in the study of lipid metabolism and related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 113826-06-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,8,2 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 113826-06:
(8*1)+(7*1)+(6*3)+(5*8)+(4*2)+(3*6)+(2*0)+(1*6)=105
105 % 10 = 5
So 113826-06-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O4S/c1-8-2-4-10(5-3-8)15(11,12)14-7-9-6-13-9/h2-5,9H,6-7H2,1H3
113826-06-5Relevant articles and documents
Asymmetric epoxidation of allyl alcohol: Efficient routes to homochiral β-adrenergic blocking agents
Klunder,Soo Ko,Sharpless
, p. 3710 - 3712 (1986)
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An Unexpected Transannular [4+2] Cycloaddition during the Total Synthesis of (+)-Norcembrene 5
Breunig, Michael,Gaich, Tanja,Yuan, Po
supporting information, p. 5521 - 5525 (2020/02/20)
We report a concise and versatile total synthesis of the diterpenoid (+)-norcembrene 5 from simple building blocks. Ring-closing metathesis and an auxiliary-directed 1,4-addition are the key steps of our synthetic route. During the synthesis, an unprecede
Method for manufacturing optically active cyclic ether ester derivative
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Paragraph 0100; 0101; 0102, (2017/01/02)
The invention provides a method for simply and selectively manufacturing an optically active cyclic ether aryl sulfonic acid ester with an inexpensively obtained racemate as the raw material. The method for manufacturing the cyclic ether aryl sulfonic acid ester comprises the steps of with the existence of optically active bisoxazoline ligand, lewis acid compound, alkali and organic solvent, aryl sulfonyl halide and hydroxymethyl cyclic ether are subjected to the racemate reaction to obtain an optically active cyclic ether aryl sulfonic acid ester. Preferably glycidyl or 2-hydroxymethyl tetrahydrofuran is adopted as the above hydroxymethyl cyclic ether.
