113976-32-2

Basic information

• Product Name: 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-decanedioic acid dimethyl ester
• Synonyms: 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-decanedioic acid dimethyl ester
• CAS NO: 113976-32-2
• Molecular Weight: 552.633
• Mol File: 113976-32-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-decanedioic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-decanedioic acid dimethyl ester(113976-32-2)
• EPA Substance Registry System: 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-decanedioic acid dimethyl ester(113976-32-2)

Safety Data

• Hazardous Substances Data: 113976-32-2(Hazardous Substances Data)

Upstream product

• 113976-39-9 2-bromo-decanedioic acid dimethyl ester 
• 818-88-2 sebacic acid mono methyl ester 
• 14065-32-8 methyl 10-chloro-10-oxodecanoate 
• 19741-14-1 4-[(2,4-diaminopteridin-6-ylmethyl)methylamino]benzoic acid 
• 5686-32-8 2-Amino-decanedioic acid dimethyl ester; hydrochloride 

Downstream Products

• 113976-24-2 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-decanedioic acid 

Relevant articles and documents

Methotrexate analogues. 34. Replacement of the glutamate moiety in methotrexate and aminopterin by long-chain 2-aminoalkanedioic acids

Eight previously unreported methotrexate (MTX) and aminopterin (AMT) analogues with the L-glutamate moiety replaced by DL-2-aminoalkanedioic acids containing up to 10 CH2 groups were synthesized from 4-amino-4-deoxy-N10-methylpteroic