114108-90-6

Basic information

• Product Name: (4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER
• Synonyms: (4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER;(4-Fluoro-2-fluoro-phenyl)-carbamic acid ethyl ester;ETHYL 4-CHLORO-2-FLUOROPHENYLCARBAMATE
• CAS NO: 114108-90-6
• Molecular Formula: C₉H₉ClFNO₂
• Molecular Weight: 217.62
• Mol File: 114108-90-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 228.5°C at 760 mmHg
• Flash Point: 92°C
• Appearance: /
• Density: 1.347g/cm³
• Vapor Pressure: 0.073mmHg at 25°C
• Refractive Index: 1.554
• PKA: 11.90±0.70(Predicted)
• CAS DataBase Reference: (4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER(114108-90-6)
• EPA Substance Registry System: (4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER(114108-90-6)

Safety Data

• Hazardous Substances Data: 114108-90-6(Hazardous Substances Data)

Usage

Description

(4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER is a chemical compound that belongs to the carbamate class, characterized by its chloro and fluoro substituents on the phenyl ring. It is an ethyl ester derivative of (4-chloro-2-fluoro-phenyl)carbamic acid and is commonly used in organic synthesis.

Uses

Used in Pharmaceutical Industry:
(4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER is used as a reactant in the synthesis of various pharmaceutical compounds due to its unique structural features and reactivity.
Used in Agricultural Industry:
(4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER is used as a reactant in the development of pesticides and herbicides, contributing to its potential applications in crop protection and management.
Used in Chemical Synthesis:
(4-CHLORO-2-FLUORO-PHENYL)-CARBAMIC ACID ETHYL ESTER is used as a versatile building block in organic synthesis, allowing for the creation of a wide range of chemical products with diverse applications.

InChI:InChI=1/C9H9ClFNO2/c1-2-14-9(13)12-8-4-3-6(10)5-7(8)11/h3-5H,2H2,1H3,(H,12,13)

Upstream product

• 57946-56-2 2-fluoro-4-chloroaniline 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 145858-70-4 5-tert-Butyl-3-(4-chloro-2-fluoro-phenyl)-3H-oxazol-2-one 
• 145859-26-3 3-(4-Chloro-2-fluoro-phenyl)-5-(1-ethyl-1-methyl-propyl)-3H-oxazol-2-one 
• 114136-65-1 3-(4-chloro-2-fluorophenyl)-6-methyl-2,4(1H,3H)-pyrimidinedione 
• 114136-63-9 3-(4-chloro-2-fluorophenyl)-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 
• 114136-76-4 2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]aniline 
• 218939-54-9 5-tert-butyl-4,5-dichloro-3-(4-chloro-2-fluoro-phenyl)-oxazolidin-2-one 

Relevant articles and documents

Synthesis of Cyclopropyl Ester and Amide Substituted Pyrimidinediones as Protoporphyrinogen Oxidase-Inhibiting Herbicides

The protoporphyrinogen oxidase (PPO) enzyme is involved in the biosynthesis of chlorophyll and is an important target in research for development of new herbicides. In this study, new pyrimidinedione compounds with thioester tail group containing cyclopropyl moiety are synthesized from the commercially available 2-(1-(mercaptomethyl)cyclopropyl)acetic acid. The herbicidal activity of the synthesized compounds is also evaluated. Most of the synthesized compounds exhibit herbicidal activities against both monocot and dicot weeds. In particular, 10a showed similar activity to the control material, Saflufenacil. And when against the monocot weeds, Echinochloa crusgalli and Digitaria sanguinalis, 10a shows superior activity to Saflufenacil.