1141461-25-7Relevant articles and documents
A convenient, one-step synthesis of benzyl (Ar) ureas of the type ArCH 2NHCONHR from Ar and R1OCH2NHCONHR via ureidoalkylation
Meece, F. Alex,Jayasinghe, Champika,Histand, Gary,Burns, Dennis H.
supporting information; experimental part, p. 3156 - 3159 (2009/09/05)
A method for the one-step C-ureidoalkylation of phenol, anisole, or aniline rings furnishing ArCH2NHCONHR (Ar ) benzyl) products in moderate to good yields is described. With phenol ring systems, higher yields were attained when the reaction was worked up with an acidic ethanethiol addition to cleave any O-ureidoalkylation products that formed during the reaction.