1141498-04-5

Basic information

• Product Name: 4-(3-phenylpropoxy)butan-1-ol
• Synonyms: 4-(3-phenylpropoxy)butan-1-ol
• CAS NO: 1141498-04-5
• Molecular Weight: 208.301
• Mol File: 1141498-04-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(3-phenylpropoxy)butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-phenylpropoxy)butan-1-ol(1141498-04-5)
• EPA Substance Registry System: 4-(3-phenylpropoxy)butan-1-ol(1141498-04-5)

Safety Data

• Hazardous Substances Data: 1141498-04-5(Hazardous Substances Data)

Upstream product

• 110-63-4 Butane-1,4-diol 
• 637-59-2 1-Bromo-3-phenylpropane 
• 1141498-13-6 1-{3-[4-(4-iodo-3-methoxy-3-methylbutoxy)butoxy]propyl}benzene 

Downstream Products

• 94749-45-8 1-[3-(4-bromobutoxy)propyl]benzene 

Relevant articles and documents

Synthesis of trans-2-Substituted Cyclopropylamines from α-Chloroaldehydes

Cyclopropylamines are prevalent in pharmaceuticals and agrochemicals. Herein, we report the synthesis of trans-2-substituted cyclopropylamines in high diastereoselectivity from readily available α-chloroaldehydes. The reaction proceeds via trapping of an electrophilic zinc homoenolate with an amine followed by ring closure to generate the cyclopropylamine. We have also observed that cyclopropylamine cis/trans-isomerization occurs in the presence of zinc halide salts and that this process can be turned off by the addition of a polar aprotic cosolvent.