1141929-15-8

Basic information

• Product Name: (S)-ethyl 2-{[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]amino}-4-methylpentanoate
• Synonyms: (S)-ethyl 2-{[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]amino}-4-methylpentanoate
• CAS NO: 1141929-15-8
• Molecular Weight: 396.247
• Mol File: 1141929-15-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-ethyl 2-{[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]amino}-4-methylpentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-ethyl 2-{[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]amino}-4-methylpentanoate(1141929-15-8)
• EPA Substance Registry System: (S)-ethyl 2-{[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]amino}-4-methylpentanoate(1141929-15-8)

Safety Data

• Hazardous Substances Data: 1141929-15-8(Hazardous Substances Data)

Upstream product

• 2743-60-4 L-Leucine ethyl ester 
• 1112233-60-9 (1R)-1-(4-bromophenyl)-2,2,2-trifluoroethyl trifluoromethanesulfonate 

Relevant articles and documents

A practical enantioselective synthesis of odanacatib, a potent cathepsin K inhibitor, via triflate displacement of an α-Trifluoromethylbenzyl triflate

An enantioselective synthesis of the Cathepsin K inhibitor odanacatib (MK-0822) 1 is described. The key step involves the novel stereospecific S N2 triflate displacement of a chiral α-trifluoromethylbenzyl triflate 9a with (S)-γ-fluoroleucine e