114258-56-9

Basic information

• Product Name: 4-(3-fluorophenyl)-1-piperazinoethanol
• Synonyms: 4-(3-fluorophenyl)-1-piperazinoethanol
• CAS NO: 114258-56-9
• Molecular Weight: 224.278
• Mol File: 114258-56-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-fluorophenyl)-1-piperazinoethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-fluorophenyl)-1-piperazinoethanol(114258-56-9)
• EPA Substance Registry System: 4-(3-fluorophenyl)-1-piperazinoethanol(114258-56-9)

Safety Data

• Hazardous Substances Data: 114258-56-9(Hazardous Substances Data)

Downstream Products

• 103074-93-7 2-(2-{2-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-ethoxy}-phenyl)-thiazolidine-3-carbothioic acid phenylamide 
• 103076-05-7 N-acetyl-2-(2-(2-(4-(3-fluorophenyl)piperazino)ethoxy)phenyl)-N-methylthiazolidine-3-thiocarboxamide 
• 103076-03-5 N-acetyl-N-methyl-2-{2-[2-(4-(3-fluorophenyl)piperazin-1-yl)ethyloxy]phenyl}thiazolidine-3-carboxamide 
• 103075-01-0 N-acetyl-2-{2-[2-(4-(3-fluorophenyl)piperazin-1-yl)ethyloxy]phenyl}thiazolidine-3-carbothioamide 
• 103074-91-5 2-(2-{2-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-ethoxy}-phenyl)-thiazolidine-3-carbothioic acid butylamide 
• 103074-85-7 2-(2-{2-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-ethoxy}-phenyl)-thiazolidine-3-carboxylic acid butylamide 
• 103074-89-1 2-(2-{2-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-ethoxy}-phenyl)-thiazolidine-3-carbothioic acid ethylamide 
• 103074-83-5 2-(2-{2-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-ethoxy}-phenyl)-thiazolidine-3-carboxylic acid ethylamide 
• 103074-30-2 2-(2-{3-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-thiazolidine-3-carbothioic acid methylamide 
• 103072-86-2 2-(2-{2-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-ethoxy}-phenyl)-thiazolidine-3-carbothioic acid methylamide 
• 103072-83-9 N-methyl-2-{2-[2-(4-(3-fluorophenyl)piperazin-1-yl)ethyloxy]phenyl}thiazolidine-3-carboxamide 
• 103076-20-6 2-(2-(2-(4-fluorophenyl)piperazino)ethoxy)thiazolizine-3-thiocarboxamide 
• 103076-64-8 2-{3-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-propoxy}-benzaldehyde 
• 103076-71-7 2-{2-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-ethoxy}-benzaldehyde 

Relevant articles and documents

Novel aminoalkylthio derivatives of triazolopyridine or triazoloquinoline, the processes for their preparation, and drugs, useful especially as analgesics, in which they are present

The present invention relates to novel compounds corresponding to the formula: STR1 in which: n represents an integer between 1 and 8 and optimally 2 or 3; (CH2)n --N can also form a ring or a heterocycle, for example having 5 to 7 atoms and preferably 6 atoms; R1 and R2 can represent hydrogen or a lower alkyl having 1 to 5 carbon atoms or can form, together with the nitrogen, a ring such as pyrrolidine, piperidine, morpholine, thiomorpholine, phenyltetrahydropyridine, piperazine or piperazine N-substituted by an alkyl, a phenyl or a heterocycle; in the case of the phenyltetrahydropyridines and the phenylpiperazines or heteroarylpiperazines, the phenyl or the heterocycle may or may not be substituted by halogens or methoxy, thiomethyl, hydroxyl, nitro, amino, cyano, lower alkyl, trifluoromethyl or trichloromethyl groups; and R3, R4 and R5 can represent hydrogen, a lower alkyl, a hydroxyalkyl or hydroxybenzyl group, a halogen, a trifluoromethyl, a methoxy, a thiomethyl or a nitro or two of them can form a ring, in particular a phenyl in the case of the triazoloquinolines or the triazoloisoquinolines; and the non-toxic acid addition salts. These products are useful as drugs and possess analgesic properties, acting especially on the central nervous system as minor tranquilizers.