1142936-98-8Relevant articles and documents
Triazolo pyridine compound and preparation method, medicinal composition and application thereof
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Paragraph 0059; 0066-0067, (2020/05/08)
The invention discloses a triazolo pyridine compound as well as a preparation method, a medicinal composition and application thereof. The compound is selected from a compound shown in a general formula I, or a tautomer, an enantiomer, a diastereoisomer,
Triazolopyridines as selective JAK1 inhibitors: From hit identification to GLPG0634
Menet, Christel J.,Fletcher, Stephen R.,Van Lommen, Guy,Geney, Raphael,Blanc, Javier,Smits, Koen,Jouannigot, Nolwenn,Deprez, Pierre,Van Der Aar, Ellen M.,Clement-Lacroix, Philippe,Lepescheux, Liên,Galien, René,Vayssiere, Béatrice,Nelles, Luc,Christophe, Thierry,Brys, Reginald,Uhring, Muriel,Ciesielski, Fabrice,Van Rompaey, Luc
, p. 9323 - 9342 (2015/01/09)
Janus kinases (JAK1, JAK2, JAK3, and TYK2) are involved in the signaling of multiple cytokines important in cellular function. Blockade of the JAK-STAT pathway with a small molecule has been shown to provide therapeutic immunomodulation. Having identified
[1,2,4]TRIAZOLO[1,5-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS AND THEIR USE
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Page/Page column 240, (2009/05/30)
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain triazolo compounds (referred to herein as TAZ compounds), and especially certain [1,2,4]triazolo[1,5-a]pyridine and [1,2,4]triazolo[1,5-c]pyri