1144034-89-8Relevant articles and documents
A convenient synthetic method for fluorine-containing 4- alkoxydihydrobenzo[b][1,4]diazepinols and 3H-benzo[b][1,4]diazepines by the reaction of β-trifluoroacetylketene acetals with 1,2-phenylenediamines
Ota, Norio,Okada, Etsuji,Terai, Naoya,Miyamura, Tomomi,Shibata, Dai,Sakata, Tsuneaki
, p. 983 - 990 (2009)
β-Trifluoroacetylketene dialkyl acetals (3 and 5) reacted easily with various 1,2-phenylenediamines to give novel 4-alkoxy-2-trifluoromethyl-2,3- dihydro-1H-benzo[b][1,4]diazepinols (6 and 8) in moderate to high yields. Dehydration of 6 and 8 proceeded th