1144035-86-8

Basic information

• Product Name: 2-(((benzylcarbamoyl)amino)(prop-2-en-1-yl)amino)acetic acid
• Synonyms: 2-(((benzylcarbamoyl)amino)(prop-2-en-1-yl)amino)acetic acid
• CAS NO: 1144035-86-8
• Molecular Weight: 263.296
• Mol File: 1144035-86-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(((benzylcarbamoyl)amino)(prop-2-en-1-yl)amino)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(((benzylcarbamoyl)amino)(prop-2-en-1-yl)amino)acetic acid(1144035-86-8)
• EPA Substance Registry System: 2-(((benzylcarbamoyl)amino)(prop-2-en-1-yl)amino)acetic acid(1144035-86-8)

Safety Data

• Hazardous Substances Data: 1144035-86-8(Hazardous Substances Data)

Usage

Type of compound

synthetic chemical compound

Potential applications

medical research and drug development

Contains

benzylcarbamoyl group, prop-2-en-1-ylamino group, and acetic acid moiety

Used as

reagent in biochemical research

Possible properties

antitumor and antiviral

Studied for potential use in

treatment of Parkinson's disease and as an inhibitor for the enzyme dihydroorotate dehydrogenase

Additional information

further research is needed to fully understand the potential uses and effects of BAPA.

Upstream product

• 637-80-9 ethyl 2-hydrazinylacetate 
• 106-95-6 allyl bromide 
• 3173-56-6 benzyl isothiocyanate 
• 671198-40-6 ethyl 2-(1-allylhydrazinyl)acetate 
• 1198777-76-2 ethyl 2-(1-allyl-2-(benzylcarbamoyl)hydrazinyl)acetate 

Downstream Products

• 1373137-80-4 (S)-2-allyl-N-benzyl-2-(2-((3-(4-(tert-butoxy)phenyl)-1-(((3-cyano-1-methyl-1H-indol-7-yl)methyl)(2,2-diethoxyethyl)amino)-1-oxopropan-2-yl)amino)-2-oxoethyl)hydrazinecarboxamide 
• 1373135-61-5 C₄₁H₄₈N₈O₅ 
• 1373137-81-5 (6S,9aS)-2-allyl-N-benzyl-8-((3-cyano-1-methyl-1H-indol-7-yl)methyl)-6-(4-hydroxybenzyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]-triazine-1-carboxamide 
• 1373137-82-6 ethyl 7-(((6S,9aS)-2-allyl-1-(benzylcarbamoyl)-6-(4-hydroxybenzyl)-4,7-dioxohexahydro-1H-pyrazino[2,1-c][1,2,4]-triazin-8(2H)-yl)methyl)-1-methyl-1H-indole-3-carboxylate 
• 1373137-83-7 7-(((6S,9aS)-2-allyl-1-(benzylcarbamoyl)-6-(4-hydroxybenzyl)-4,7-dioxohexahydro-1H-pyrazino[2,1-c][1,2,4]-triazin-8(2H)-yl)methyl)-1-methyl-1H-indole-3-carboxylic acid 
• 1251834-08-8 C₃₈H₄₃IN₆O₄ 
• 1373137-84-8 (6S,9aS)-2-allyl-8-((3-(4-aminophenyl)-1-methyl-1H-indol-7-yl)methyl)-N-benzyl-6-(4-(tert-butoxy)benzyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide 
• 1373134-54-3 (6S,9aS)-2-allyl-N-benzyl-6-(4-hydroxybenzyl)-8-((3-(4-(3-(6-methoxypyridin-3-yl)ureido)phenyl)-1-methyl-1H-indol-7-yl)methyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]-triazine-1-carboxamide 
• 1373137-85-9 (6S,9aS)-2-allyl-8-((3-(6-aminopyridin-3-yl)-1-methyl-1H-indol-7-yl)methyl)-N-benzyl-6-(4-(tert-butoxy)benzyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide 
• 1373134-55-4 (6S,9aS)-2-allyl-N-benzyl-6-(4-hydroxybenzyl)-8-((1-methyl-3-(6-(3-phenylureido)pyridine-3-yl)-1H-indol-7-yl)methyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]-triazine-1-carboxamide 
• 1251834-07-7 C₄₂H₅₅IN₆O₆ 
• 1251834-01-1 C₄₄H₅₈N₆O₇ 

Relevant articles and documents

NOVEL COMPOUND OF A REVERSE-TURN MIMETIC AND A PRODUCTION METHOD AND USE THEREFOR

This invention relates to novel compounds of reverse-turn mimetics, having pyrazino-triazinone as a basic framework, and a method of preparing the same, and the use thereof to treat diseases such as cancer, in particular, acute myeloid leukemia.

NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF

Disclosed are novel reverse turn mimetics based on the framework of pyrazino-triazinone, and the use thereof in the treatment of cancers, particularly, acute myeloid leukemia. A method is also provided for manufacturing the reverse turn mimetics on a mass scale.