114482-86-9

Basic information

• Product Name: Baicalin-7-diglucoside
• Synonyms: Baicalin-7-diglucoside;Oroxin B;7-[(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]-5,6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one;Baicalein 7-O-beta-gentiobioside;Baicalein 7-O-diglucoside;Baicalein-7-O-gentiobioside;Oroxin B, 98%, from Oroxylum indicum
• CAS NO: 114482-86-9
• Molecular Formula: C27H30O15
• Molecular Weight: 594.5181
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 114482-86-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 957.5±65.0 °C(Predicted)
• Appearance: /
• Density: 1.76
• PKA: 5.91±0.40(Predicted)
• CAS DataBase Reference: Baicalin-7-diglucoside(CAS DataBase Reference)
• NIST Chemistry Reference: Baicalin-7-diglucoside(114482-86-9)
• EPA Substance Registry System: Baicalin-7-diglucoside(114482-86-9)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 114482-86-9(Hazardous Substances Data)

Usage

Description

Baicalin-7-diglucoside is a flavonoid compound derived from the roots of the Scutellaria baicalensis plant, commonly known as the Chinese skullcap. It is a bioactive compound with various pharmacological properties, including anti-inflammatory, antioxidant, and anti-cancer activities. Baicalin-7-diglucoside is characterized by its unique chemical structure, which consists of two glucose molecules attached to the baicalin molecule.

Uses

Used in Traditional Chinese Medicine:
Baicalin-7-diglucoside is used as a therapeutic agent for various inflammatory and pain-related conditions due to its anti-inflammatory and analgesic properties. It is an essential component in the treatment of various ailments, such as fever, respiratory infections, and gastrointestinal disorders.
Used in Anticancer Applications:
Baicalin-7-diglucoside is used as an anticancer agent, particularly against solid malignancies such as liver, breast, lung, pancreatic, colorectal, and ovarian cancers. It modulates several oncological signaling pathways, exerting inhibitory effects on tumor growth and progression. Additionally, it demonstrates synergistic anticancer effects when combined with conventional chemotherapeutic drugs, enhancing chemo-sensitivity and efficacy in resistant cases.
Used in Drug Delivery Systems:
To overcome the limitations of Baicalin-7-diglucoside, such as poor solubility and bioavailability, novel drug delivery systems have been developed to enhance its applications and efficacy against cancer cells. Various organic and metallic nanoparticles have been employed as carriers for Baicalin-7-diglucoside delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes.
Used in Pharmaceutical Industry:
Baicalin-7-diglucoside is used as a key ingredient in the development of new drugs for the treatment of various diseases, including cancer, inflammation, and oxidative stress-related conditions. Its diverse pharmacological properties make it a promising candidate for drug discovery and development.
Used in Nutraceutical Industry:
Baicalin-7-diglucoside is used as an active ingredient in the formulation of dietary supplements and functional foods, targeting health-conscious consumers seeking natural alternatives for maintaining overall health and well-being. Its antioxidant and anti-inflammatory properties contribute to the prevention of various diseases and the promotion of a healthy immune system.