1145683-40-4

Basic information

• Product Name: 2-{5-[1-(3,4-Difluoro-phenyl)-piperidin-3-yl]-4'-trifluoromethyl-biphenyl-3-yl}-4-methyl-pentanoic acid ethyl ester
• Synonyms: 2-{5-[1-(3,4-Difluoro-phenyl)-piperidin-3-yl]-4'-trifluoromethyl-biphenyl-3-yl}-4-methyl-pentanoic acid ethyl ester
• CAS NO: 1145683-40-4
• Molecular Weight: 559.619
• Mol File: 1145683-40-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{5-[1-(3,4-Difluoro-phenyl)-piperidin-3-yl]-4'-trifluoromethyl-biphenyl-3-yl}-4-methyl-pentanoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{5-[1-(3,4-Difluoro-phenyl)-piperidin-3-yl]-4'-trifluoromethyl-biphenyl-3-yl}-4-methyl-pentanoic acid ethyl ester(1145683-40-4)
• EPA Substance Registry System: 2-{5-[1-(3,4-Difluoro-phenyl)-piperidin-3-yl]-4'-trifluoromethyl-biphenyl-3-yl}-4-methyl-pentanoic acid ethyl ester(1145683-40-4)

Safety Data

• Hazardous Substances Data: 1145683-40-4(Hazardous Substances Data)

Upstream product

• 1145683-19-7 4-Methyl-2-(5-piperidin-3-yl-4'-trifluoromethyl-biphenyl-3-yl)-pentanoic acid ethyl ester 
• 64248-58-4 1,2-difluoro-4-iodo-benzene 

Relevant articles and documents

PIPERIDINYL AND PIPERAZINYL MODULATORS OF y-SECRETASE

The present invention relates to compounds of Formula I as shown below, wherein the definitions of Het, R0, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.