114650-46-3

Basic information

• Product Name: Benzenamine, 4-methoxy-2-(1-methylethyl)- (9CI)
• Synonyms: Benzenamine, 4-methoxy-2-(1-methylethyl)- (9CI)
• CAS NO: 114650-46-3
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.2322
• Product Categories: ISOPROPYL
• Mol File: 114650-46-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 267.5±28.0 °C(Predicted)
• Appearance: /
• Density: 0.996±0.06 g/cm3(Predicted)
• PKA: 5.02±0.10(Predicted)
• CAS DataBase Reference: Benzenamine, 4-methoxy-2-(1-methylethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-methoxy-2-(1-methylethyl)- (9CI)(114650-46-3)
• EPA Substance Registry System: Benzenamine, 4-methoxy-2-(1-methylethyl)- (9CI)(114650-46-3)

Safety Data

• Hazardous Substances Data: 114650-46-3(Hazardous Substances Data)

Upstream product

• 1308803-37-3 2-isopropenyl-4-methoxynitrobenzene 
• 98447-30-4 2-bromo-4-methoxy-1-nitrobenzene 
• 700-36-7 2-bromo-4-fluoronitrobenzene 
• 100-17-4 para-methoxynitrobenzene 
• 1068-55-9 isopropylmagnesium chloride 
• 13522-86-6 2-iso-propyl-4-methoxyphenol 
• 88-69-7 2-(1-methylethyl)phenol 

Downstream Products

• 1085267-11-3 N-(2-isopropyl-4-methoxyphenyl)antranilic acid 

Relevant articles and documents

PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR

The present disclosure provides pyrimidine compounds of Formula 1 and uses thereof, for example, for the potential treatment of diseases associated with P2X purinergic receptors. In certain aspects, the present disclosure provides P2X3 and/or P2X2/3 antagonists which are useful, for example, for the potential treatment of visceral organ, cardiovascular and pain-related diseases, conditions and disorders.

ONE-POT CHEMOSELECTIVE REDUCTIVE ALKYLATION OF NITROARENES: A NEW GENERAL METHOD OF SYNTHESIS OF ALKYLANILINES.

A New facile and general synthesis of alkylanilines by one-pot reductive alkylation of nitroarenes is reported.This method is based on the "in situ" reduction by hydrides (LiAlH4 or NaBH4) in the presence of catalytic amounts of Pd/C, of nitronate adducts arising from the conjugate addition of Grignard reagents to mononitroarenes.LiAlH4 showed to be a more efficient but less selective reducing agent than NaBH4.The reaction can be successfully applied to mono, homo and hetero bicyclic systems and allows to introduce a large variety of alkyl chains without isomerisation phenomena.