114676-67-4

Basic information

• Product Name: (2S,4R)-1-Boc-4-(tert-butyldiMethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine
• Synonyms: (2S,4R)-1-Boc-4-(tert-butyldiMethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine;4-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-pyrrolidine-1-carboxylic acid;(2S,4R)-tert-Butyl 4-((tert-butyldimethylsilyl)oxy)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
• CAS NO: 114676-67-4
• Molecular Formula: C₁₆H₃₃NO₄Si
• Molecular Weight: 331.52302
• Mol File: 114676-67-4.mol
• Article Data: 28

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (2S,4R)-1-Boc-4-(tert-butyldiMethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-1-Boc-4-(tert-butyldiMethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine(114676-67-4)
• EPA Substance Registry System: (2S,4R)-1-Boc-4-(tert-butyldiMethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine(114676-67-4)

Safety Data

• Hazardous Substances Data: 114676-67-4(Hazardous Substances Data)

Usage

General Description

"(2S,4R)-1-Boc-4-(tert-butyldiMethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine" is a chemical compound containing a pyrrolidine ring with a Boc (tert-butoxycarbonyl) protecting group at the 1-position and a tert-butyldimethylsilyloxy group at the 4-position. Additionally, it has a hydroxymethyl group attached to the 2-position of the pyrrolidine ring. (2S,4R)-1-Boc-4-(tert-butyldiMethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine is commonly used as a building block in organic synthesis, particularly in the construction of complex molecules and natural products. The Boc protecting group can be removed under mild acidic conditions, allowing for further manipulation of the molecule. The tert-butyldimethylsilyloxy group serves as a protecting group for the alcohol functionality, providing stability during chemical reactions. Overall, "(2S,4R)-1-Boc-4-(tert-butyldiMethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine" is a versatile and useful compound in the field of organic chemistry.

Upstream product

• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 13726-69-7 (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 117811-66-2 (2S,4R)-4-t-butyldimethylsilyloxy-2-hydroxymethylpyrrolidine 
• 104795-11-1 (2S,4R)-1-benzyloxycarbonyl-4-<(tert-butyldimethylsilyl)oxy>-2-(hydroxymethyl)pyrrolidine 
• 151953-64-9 (3R,5S)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}pyrrolidine-3-ol 
• 1499-56-5 (R)-4-hydroxy-L-proline ethyl ester 
• 753014-18-5 1-tert-butyl 2-ethyl (2S,4R)-4-{[tert-butyl (dimethyl)silyl]oxy} pyrrolidine-1,2-dicarboxylate 
• 51-35-4 4R-4-hydroxyproline 
• 74844-91-0 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 
• 114676-91-4 1-tert-butyl 2-methyl (2S,4R)-4-{[tert-butyl(dimethyl)silyl]oxy}pyrrolidine-1,2-dicarboxylate 
• 1159609-88-7 N-t-butoxycarbonyl-4-(R)-t-butyldimethylsilyloxy proline methyl ester 
• 7757-82-6 sodium sulfate 

Downstream Products

• 857651-10-6 tert-butyl (2S,4R)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-({[(4-methylphenyl)-sulfonyl]-oxy}methyl)pyrrolidine-1-carboxylate 
• 1257235-37-2 (1-{1-[4-benzylcarbamoyl-6-(4-fluoro-benzyloxy)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propylcarbamoyl}-ethyl)-methyl-carbamic acid benzyl ester 
• 1257235-00-9 (1-{1-[6-(3,4-difluoro-phenoxy)-4-(tetrahydro-pyran-4-yl)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propylcarbamoyl}-ethyl)-methyl-carbamic acid benzyl ester 
• 1257235-51-0 {1-[1-(6-benzylcarbamoyloxy-4-isopropylcarbamoyl-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl)-2,2-dimethyl-propylcarbamoyl]-ethyl}-methyl-carbamic acid benzyl ester 
• 1257235-12-3 4-{2-[2-(benzyloxycarbonyl-methyl-amino)-propionylamino]-3,3-dimethyl-butyryl}-3-(3,4-difluoro-phenoxy)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid tert-butyl ester 
• 1257235-08-7 (1-{1-[6-(3,4-difluoro-phenoxy)-4-(tetrahydro-pyran-4-yl)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propylcarbamoyl}-ethyl)-methyl-carbamic acid benzyl ester 
• 1257235-20-3 (1-{1-[6-(3,4-difluoro-phenoxy)-4-methylcarbamoyl-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propylcarbamoyl}-ethyl)-methyl-carbamic acid benzyl ester 
• 1257235-33-8 4-{2-[2-(benzyloxycarbonyl-methyl-amino)-propionylamino]-3,3-dimethyl-butyryl}-3-(4-fluoro-benzyloxy)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid tert-butyl ester 
• 1257235-16-7 (1-{1-[6-(3,4-difluoro-phenoxy)-4-methanesulfonyl-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propylcarbamoyl}-ethyl)-methyl-carbamic acid benzyl ester 
• 1257235-18-9 (1-{1-[4-acetyl-6-(3,4-difluoro-phenoxy)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propylcarbamoy1}-ethyl)-methyl-carbamic acid benzy1 ester 
• 1257233-67-2 4-[3,3-dimethyl-2-(2-methylamino-propionylamino)-butyryl]-3-(4-fluorobenzyloxy)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzylamide 
• 1257234-96-0 {1-[6-(3,4-difluoro-phenoxy)-4-(tetrahydro-pyran-4-yl)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propyl}carbamic acid benzyl ester 
• 1257235-14-5 (1-{1-[6-(3,4-difluoro-phenoxy)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propylcarbamoyl}-ethyl)-methyl-carbamic acid benzyl ester 
• 1257234-80-2 4-{2-[2-(benzyloxycarbonyl-methyl-amino)-propionylamino]-3-methyl-butyryl}-3-phenoxy-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid tert-butyl ester 

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