1147320-04-4Relevant articles and documents
A Tandem conjugate addition/cyclization protocol for the asymmetric synthesis of 2-Aryl-4-aminotetrahydroquinoline-3-carboxylic acid derivatives
Davies, Stephen G.,Mujtaba, Nadeam,Roberts, Paul M.,Smith, Andrew D.,Thomson, James E.
supporting information; experimental part, p. 1959 - 1962 (2009/09/25)
Condensation of fert-butyl (E)-3-(2'-aminophenyl)propenoate with a range of aromatic and heteroaromatic aldehydes gives the corresponding imines as single diastereoisomers (>98% de). Addition of lithium (R)-W-benzyl-W-(α- methylbenzyl)amide initiates a ta