114744-90-0

Basic information

• Product Name: ((1S,2R)-2-Hydroxy-1-methyl-butyl)-carbamic acid benzyl ester
• Synonyms: ((1S,2R)-2-Hydroxy-1-methyl-butyl)-carbamic acid benzyl ester
• CAS NO: 114744-90-0
• Molecular Weight: 237.299
• Mol File: 114744-90-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ((1S,2R)-2-Hydroxy-1-methyl-butyl)-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((1S,2R)-2-Hydroxy-1-methyl-butyl)-carbamic acid benzyl ester(114744-90-0)
• EPA Substance Registry System: ((1S,2R)-2-Hydroxy-1-methyl-butyl)-carbamic acid benzyl ester(114744-90-0)

Safety Data

• Hazardous Substances Data: 114744-90-0(Hazardous Substances Data)

Upstream product

• 114744-83-1 (S)-benzyl (1-(N,O-dimethylhydroxylamine)-1-oxopropan-2-yl)carbamate 
• 28819-05-8 (S)-2-benzyloxycarbonylamino-propionic acid methyl ester 
• 82353-55-7 benzyl (S)-1-oxopropan-2-ylcarbamate 
• 925-90-6 ethylmagnesium bromide 
• 114744-86-4 ((S)-1-Methyl-2-oxo-butyl)-carbamic acid benzyl ester 

Relevant articles and documents

ALUMINUM-MEDIATED ONE-POT CONVERSION OF α-AMINO ACID ESTERS TO THREO 2-AMINO ALCOHOLS WITH HIGH DIASTEREOSELECTIVITY

Reduction of N-Cbz α-amino acid esters with DIBAl-H, followed by treatment with Grignard reagent in a one-pot manner gave the corresponding threo 2-amino alcohols with high diastereoselectivity without racemization. KEYWORDS 2-amino alcohol; α-amino acid ester; DIBAL-H reduction; α-amino aldehyde; chelation controll; diastereoselective synthesis; one-pot synthesis