1148119-15-6

Basic information

• Product Name: (E)-3-(3-hydroxy-4-methoxybenzylidene)-6-methoxyindolin-2-one
• Synonyms: (E)-3-(3-hydroxy-4-methoxybenzylidene)-6-methoxyindolin-2-one
• CAS NO: 1148119-15-6
• Molecular Weight: 297.31
• Mol File: 1148119-15-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-3-(3-hydroxy-4-methoxybenzylidene)-6-methoxyindolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(3-hydroxy-4-methoxybenzylidene)-6-methoxyindolin-2-one(1148119-15-6)
• EPA Substance Registry System: (E)-3-(3-hydroxy-4-methoxybenzylidene)-6-methoxyindolin-2-one(1148119-15-6)

Safety Data

• Hazardous Substances Data: 1148119-15-6(Hazardous Substances Data)

Upstream product

• 621-59-0 isovanillin 
• 7699-19-6 6-methoxyoxindole 

Relevant articles and documents

NOVEL BENZYLIDENE-INDOLINONE AND THEIR MEDICAL AND DIAGNOSTIC USES

The present invention relates generally to organic chemistry, biochemistry, pharmacology and medicine. More particularly, it relates to 3-benzylidene-indolin-2-one derivatives and their physiologically acceptable salts and prodrugs which modulate the activity of protein kinases ( PKs ), especially protein tyrosine kinase, and, therefore, are expected to exhibit a salutary effect against disorders related to abnormal PK activity. The present invention is further directed to methods of using of these compounds, alone or in combination with other therapeutic agents, for the alleviation, prevention and/or treatment of protein kinase-mediated diseases and disorders, such as cancer.