1149379-08-7

Basic information

• Product Name: ethyl (1S,1aS,6aR)-4-[(2',6'-dichloro-4-fluoro-2-methylbiphenyl-3-yl)methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate
• Synonyms: ethyl (1S,1aS,6aR)-4-[(2',6'-dichloro-4-fluoro-2-methylbiphenyl-3-yl)methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate
• CAS NO: 1149379-08-7
• Molecular Weight: 485.382
• Mol File: 1149379-08-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (1S,1aS,6aR)-4-[(2',6'-dichloro-4-fluoro-2-methylbiphenyl-3-yl)methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (1S,1aS,6aR)-4-[(2',6'-dichloro-4-fluoro-2-methylbiphenyl-3-yl)methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate(1149379-08-7)
• EPA Substance Registry System: ethyl (1S,1aS,6aR)-4-[(2',6'-dichloro-4-fluoro-2-methylbiphenyl-3-yl)methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate(1149379-08-7)

Safety Data

• Hazardous Substances Data: 1149379-08-7(Hazardous Substances Data)

Upstream product

• 1149379-07-6 ethyl (1S,1aS,6aR)-4-[(6-fluoro-3-iodo-2-methylbenzyl)oxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate 
• 73852-17-2 2,6-dichlorophenylboronic acid 

Downstream Products

• 1149378-86-8 (1S,1aS,6aR)-4-[(2',6'-dichloro-4-fluoro-2-methylbiphenyl-3-yl)methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylic acid 

Relevant articles and documents

ANTIDIABETIC TRICYCLIC COMPOUNDS

Tricyclic compounds containing a cyclopropanecarboxylic acid fused to a bicyclic ring, including pharmaceutically acceptable salts, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.