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1150560-54-5

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  • 1-(2-fluoro-6-(trifluoromethyl)benzyl)-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione

    Cas No: 1150560-54-5

  • USD $ 1.2-5.0 / Kiloliter

  • 5 Kiloliter

  • 3000 Metric Ton/Month

  • Chemwill Asia Co., Ltd.
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1150560-54-5 Usage

Description

1-[2-Fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione is a complex organic compound with a unique molecular structure. It is characterized by the presence of a fluorine atom, a trifluoromethyl group, and an iodine atom, which contribute to its distinct chemical properties. 1-[2-Fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione is primarily used as a research chemical and serves as an intermediate in the synthesis of pharmaceuticals.

Uses

Used in Pharmaceutical Research:
1-[2-Fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione is used as a research chemical for the development and study of new pharmaceutical compounds. Its unique molecular structure makes it a valuable tool in the exploration of novel drug candidates and potential therapeutic applications.
Used in the Synthesis of Elagolix:
1-[2-Fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione is used as an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH). Elagolix is utilized in the treatment of endometriosis, a painful disorder that affects the uterus. The compound's role in the synthesis process highlights its importance in the development of medications for various medical conditions.

Physical Form

Solid

Check Digit Verification of cas no

The CAS Registry Mumber 1150560-54-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,0,5,6 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1150560-54:
(9*1)+(8*1)+(7*5)+(6*0)+(5*5)+(4*6)+(3*0)+(2*5)+(1*4)=115
115 % 10 = 5
So 1150560-54-5 is a valid CAS Registry Number.

1150560-54-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methylpyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1150560-54-5 SDS

1150560-54-5Relevant articles and documents

PROCESS FOR PREPARING ELAGOLIX SODIUM AND INTERMEDIATES THEREOF

-

Paragraph 0117; 0118, (2021/03/19)

The present invention provides improved processes for the preparation of elagolix and intermediates thereof. The intermediate of formula VII is achieved by a coupling reaction of a compound of formula V and a N-benzylidene protected compound of formula IV

PROCESSES TO PRODUCE ELAGOLIX

-

, (2019/06/23)

The present invention relates to a scalable process for the making of elagolix, its salts and the process of intermediate compounds.

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