115074-56-1

Basic information

• Product Name: c-4-Methylchinolizidin
• CAS NO: 115074-56-1
• Molecular Weight: 153.268
• Mol File: 115074-56-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: c-4-Methylchinolizidin(CAS DataBase Reference)
• NIST Chemistry Reference: c-4-Methylchinolizidin(115074-56-1)
• EPA Substance Registry System: c-4-Methylchinolizidin(115074-56-1)

Safety Data

• Hazardous Substances Data: 115074-56-1(Hazardous Substances Data)

Upstream product

• 90978-08-8 6-methyl-octahydro-quinolizin-4-one 
• 5504-64-3 cis-4-methylperhydroquinolizin-6-one 
• 5504-64-3 trans-4-methylperhydroquinolizin-6-one 
• 1122-70-9 2-methyl-6-vinylpyridine 
• 90874-87-6 1-(2-pyridyl)pentan-4-one 
• 100370-10-3 ethyl 4-(6-methylpyridin-2-yl)butanoate 
• 934-78-1 2-(6-methylpyridin-2-yl)-ethanol 
• 100-69-6 2-vinylpyridine 
• 57606-77-6 6-hepten-2-one oxime 
• 95448-64-9 cis-Methyl 2-(3-Cyanopropyl)-6-methylpiperidine-1-carboxylate 
• 95448-64-9 trans-Methyl 2-(3-Cyanopropyl)-6-methylpiperidine-1-carboxylate 
• 95448-68-3 cis-2-(3-Ethoxycarbonylpropyl)-6-methylpiperidine 
• 95448-61-6 N-methoxycarbonyl-6-aminohept-1-ene 
• 1462-92-6 6-methyl-2,3,4,5-tetrahydro-pyridine 

Downstream Products

• 106480-00-6 (+/-)-4t,5t-dimethyl-(9ar)-octahydro-quinolizinium; picrate 
• 106480-00-6 (+/-)-4c,5ξ-dimethyl-(9ar)-octahydro-quinolizinium; picrate 

Relevant articles and documents

-

-

Novel synthesis of indolizidines and quinolizidines

A very short synthesis of indolizidines, quinolizidines and some higher homologues was developed by alkylation of 2-methyl-1-pyrroline or 6-methyl-2,3,4,5-tetrahydropyridine with 1,3- or 1,4-dihaloalkanes, followed by reduction of the intermediate iminium salts, resulting in the desired 1-azabicyclo[m.n.0]alkanes in good yields.

Synthesis of trans-2,6-Dialkylpiperidines by Intramolecular Amidomercuration

Intramolecular amidomercuration of N-methoxycarbonyl-6-aminohept-1-ene and reaction of the resulting organomercurial with sodium borohydride in the presence of acrylonitrile or decen-3-one has been used to prepare trans-2,6-dialkylpiperidines, including solenopsin A, a constituent of the venom of the fire-ant.