1152853-28-5

Basic information

• Product Name: 2-morpholino-1-(4-(chloro)phenyl)propan-1-one
• Synonyms: 2-morpholino-1-(4-(chloro)phenyl)propan-1-one
• CAS NO: 1152853-28-5
• Molecular Weight: 253.729
• Mol File: 1152853-28-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-morpholino-1-(4-(chloro)phenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-morpholino-1-(4-(chloro)phenyl)propan-1-one(1152853-28-5)
• EPA Substance Registry System: 2-morpholino-1-(4-(chloro)phenyl)propan-1-one(1152853-28-5)

Safety Data

• Hazardous Substances Data: 1152853-28-5(Hazardous Substances Data)

Upstream product

• 6285-05-8 4'-chloropropiophenone 
• 110-91-8 morpholine 
• 877-37-2 2-bromo-1-(4-chlorophenyl)-1-propanone 
• 106-39-8 bromochlorobenzene 
• 13856-85-4 1-(4-chlorophenyl)-1-propanol 

Relevant articles and documents

Enantioselective and Diastereoselective Construction of Chiral Amino Alcohols by Iridium-f-Amphox-Catalyzed Asymmetric Hydrogenation via Dynamic Kinetic Resolution

The iridium-f-amphox-catalyzed asymmetric hydrogenation of racemic α-amino β-unfunctionalized ketones proceeds via a DKR (dynamic kinetic resolution) process for the construction of various chiral N,N-disubstituted α-amino β-unfunctionalized alcohols in quantitative yields with excellent enantioselectivities and diastereoselectivities (all products >99% ee and >99:1 dr, TON up to 100 000). Importantly, this catalytic asymmetric hydrogenation with a DKR process provided a highly efficient and powerful synthetic strategy for the preparation of key chiral intermediates of the preclinical antitumor agent (S,S)-R116010.