115378-72-8Relevant articles and documents
Diastereoselective Reduction of α-Keto Amides Having trans-2,5-Disubstituted Pyrrolidines as Chiral Auxiliaries
Kawanami, Yasuhiro,Fujita, Izumi,Taniguchi, Yoshiyuki,Katsuki, Tsutomu,Yamaguchi, Mosaru
, p. 2021 - 2024 (1987)
The reduction of α-keto amides derived from (2R,5R)-trans-2,5-bis(methoxymethoxymethyl)pyrrolidine with LiBEt3H proceeded with high diastereoselectivity (up to 99percent ds) to afford the corresponding α-hydroxy amides in good yield.The effect of added cr