115388-93-7

Basic information

• Product Name: H-PRO-AMC HBR
• Synonyms: L-PROLINE-7-AMIDO-4-METHYLCOUMARIN HBR;L-PROLINE 7-AMIDO-4-METHYL-COUMARIN HYDROBROMIDE;L-PROLINE 7-AMIDO-4-METHYLCOUMARIN HYDROBROMIDE SALT;L-PROLINE-AMC HBR;H-PRO-AMC HBR;PROLINE-AMC HBR;L-Proline7-amido-4-methycouraminhydrobromidesalt;(2S)-N-(4-METHYL-2-OXO-CHROMEN-7-YL)-2,3,4,5-TETRAHYDROPYRROLE-2-CARBOXAMIDE
• CAS NO: 115388-93-7
• Molecular Formula: C15H17BrN2O3
• Molecular Weight: 353.21
• Product Categories: Activity;Enzyme Substrates;Fluorogenic;substrate
• Mol File: 115388-93-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 532 °C at 760 mmHg
• Flash Point: 275.5 °C
• Appearance: /
• Vapor Pressure: 2.13E-11mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: H-PRO-AMC HBR(CAS DataBase Reference)
• NIST Chemistry Reference: H-PRO-AMC HBR(115388-93-7)
• EPA Substance Registry System: H-PRO-AMC HBR(115388-93-7)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 115388-93-7(Hazardous Substances Data)

Usage

Description

H-PRO-AMC HBR, also known as L-Proline 7-Amido-4-methylcoumarin Hydrobromide, is a fluorogenic substrate used for the detection of L-proline aminopeptidase. It is a colorless to off-white crystalline powder with unique chemical properties that make it suitable for various applications in different industries.

Uses

Used in Research and Development:
H-PRO-AMC HBR is used as a research tool for the detection and study of L-proline aminopeptidase, an enzyme that plays a crucial role in various biological processes. Its ability to produce a fluorescent signal upon enzymatic cleavage makes it an ideal substrate for monitoring enzyme activity and inhibition.
Used in Pharmaceutical Industry:
H-PRO-AMC HBR is used as a diagnostic agent for the development of drugs targeting L-proline aminopeptidase. By monitoring the enzyme's activity in the presence of potential inhibitors, researchers can evaluate the effectiveness of these compounds in modulating the enzyme's function.
Used in Biotechnology Industry:
H-PRO-AMC HBR is used as a reagent in the biotechnology industry for the development of biosensors and high-throughput screening assays. Its fluorescent properties allow for the rapid and sensitive detection of L-proline aminopeptidase activity, facilitating the identification of novel enzyme inhibitors and modulators.
Used in Quality Control:
H-PRO-AMC HBR is used as a quality control standard for the assessment of L-proline aminopeptidase activity in various samples. Its consistent fluorescence properties enable accurate measurement and comparison of enzyme activity across different experiments and conditions.

InChI:InChI=1/C15H16N2O3/c1-9-7-14(18)20-13-8-10(4-5-11(9)13)17-15(19)12-3-2-6-16-12/h4-5,7-8,12,16H,2-3,6H2,1H3,(H,17,19)/p+1/t12-/m0/s1