115395-16-9

Basic information

• Product Name: Butanoic acid, 3-mercapto-, (R)-
• CAS NO: 115395-16-9
• Molecular Formula: C4H8O2S
• Molecular Weight: 120.172
• Mol File: 115395-16-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 3-mercapto-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 3-mercapto-, (R)-(115395-16-9)
• EPA Substance Registry System: Butanoic acid, 3-mercapto-, (R)-(115395-16-9)

Safety Data

• Hazardous Substances Data: 115395-16-9(Hazardous Substances Data)

Upstream product

• 65058-82-4 (S)-(-)-β-methyl-β-propiolactone 

Downstream Products

• 115395-14-7 (R)-3-(Phenylthio)buttersaeure 

Relevant articles and documents

Herstellung enantiomerenreiner Derivate von 3-Amino- und 3-Mercaptobuttersaeure durch SN2-Ringoeffnung des β-Lactons und eines 1,3-Dioxanons aus der 3-Hydroxybuttersaeure

From (S)-4-methyloxetan-2-one (1), the β-butyrolactone readily available from the biopolyner (R)-polyhydroxybutyrate (PHB) and various C,N,O and S nucleophiles, the following compounds are prepared: (S)-2-hydroxy-4-octanone (3), (R)-3-aminobutanoic acid (7) and its benzyl derivative 5, (R)-3-azidobutanoic acid (6), (R)-3-mercaptobutanoic acid (10), (R)-3-(phenylthio)butanoic acid (8) and its sulfoxide 9.The (6R)-2,6-dimethyl-2-ethoxy-1,3-dioxan-4-one (4) from (R)-3-hydroxybutanoic acid undergoes SN2 ring opening with benzylamine to give the N-benzyl derivative (ent-5) of (S)-3-aminobutanoic acid in 30-40percent yield.