115511-05-2Relevant articles and documents
Renin inhibitors containing hydrophilic groups. Tetrapeptides with enhanced aqueous solubility and nanomolar potency
Bock,DiPardo,Evans,Freidinger,Rittle,Payne,Boger,Whitter,LaMont,Ulm,Blaine,Schorn,Veber
, p. 1918 - 1923 (1988)
Nineteen tetrapeptides containing statine (Sta) and 4-amino-5-cyclohexyl-3-hydroxypentanoic acid (ACHPA) were prepared. Solubility measurements of these compounds were carried out in H2O and in pH 7.4 phosphate buffer solution, and their partit