115663-39-3Relevant articles and documents
1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-pyrrolopyridines are 5-HT6 receptor ligands
Bernotas, Ronald C.,Antane, Schuyler A.,Lenicek, Steven E.,Haydar, Simon N.,Robichaud, Albert J.,Harrison, Boyd L.,Zhang, Guo Ming,Smith, Deborah,Coupet, Joseph,Schechter, Lee E.
scheme or table, p. 6935 - 6938 (2010/06/16)
1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-pyrrolopyridines were prepared. Binding assays indicated they are 5-HT6 receptor ligands, among which 6f and 6g showed high affinity for 5-HT6 receptors with Ki = 3.9 and 1.7 nM, respectively.
1-(aminoalkyl)-3-sulfonylazaindoles as 5-hydroxytryptamine-6 ligands
-
, (2008/06/13)
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
Influence of conjugation on orientation in substituted nitropyridines: Vicarious nucleophilic substitution of hydrogen with chloromethyl phenyl sulfone
Makosza,Ludwiczak
, p. 1168 - 1172 (2007/10/03)
2-Hydroxy- and 2-mercapto-5-nitropyridines as well as their O- (and S-) substituted derivatives enter Vicarious Nucleophilic Substitution of Hydrogen (VNS) with chloromethyl phenyl sulfone The orientation of the substitution can be controlled by varying the O- (or S-) substituent. The results of VNS in 4-methoxy-3-nitropyridine and 3-methoxy-2-nitropyridine are also reported.
