115765-22-5

Basic information

• Product Name: N-(2-chlorobenzylidene)cyclohexylamine
• Synonyms: N-(2-chlorobenzylidene)cyclohexylamine
• CAS NO: 115765-22-5
• Molecular Weight: 221.73
• Mol File: 115765-22-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(2-chlorobenzylidene)cyclohexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chlorobenzylidene)cyclohexylamine(115765-22-5)
• EPA Substance Registry System: N-(2-chlorobenzylidene)cyclohexylamine(115765-22-5)

Safety Data

• Hazardous Substances Data: 115765-22-5(Hazardous Substances Data)

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 108-91-8 cyclohexylamine 
• 17849-38-6 2-Chlorobenzyl alcohol 
• 7487-88-9 magnesium sulfate 

Downstream Products

• 1203-68-5 2-Phenylbenzaldehyde 
• 59059-42-6 2-butylbenzaldehyde 
• 100-52-7 benzaldehyde 
• 81522-28-3 o-<(trimethylsilyl)methyl>benzaldehyde 
• 46425-73-4 (2-chlorobenzyl)cyclohexylamine 
• 32832-95-4 2-benzylbenzaldehyde 
• 28272-96-0 2-vinylbenzaldehyde 
• 529-20-4 2-methylphenyl aldehyde 

Relevant articles and documents

Vanadium-and chromium-catalyzed dehydrogenative synthesis of imines from alcohols and amines

Vanadium(IV) tetraphenylporphyrin dichloride and chromium(III) tetraphenylporphyrin chloride have been developed as catalysts for the acceptorless dehydrogenation of alcohols. The catalysts have been applied to the direct synthesis of imines in overall good yields from a variety of alcohols and amines. The transformations are proposed to proceed by metal?ligand bifunctional pathways with an outer-sphere transfer of two hydrogen atoms from the alcohol to the metal porphyrin complexes. The results show that vanadium and chromium catalysts can also be employed for the dehydrogenation of alcohols with the release of hydrogen gas, and they may represent valuable alternatives to other catalysts based on Earth-abundant metals.

Manganese(III) Porphyrin-Catalyzed Dehydrogenation of Alcohols to form Imines, Tertiary Amines and Quinolines

Manganese(III) porphyrin chloride complexes have been developed for the first time as catalysts for the acceptorless dehydrogenative coupling of alcohols and amines. The reaction has been applied to the direct synthesis of imines, tertiary amines and quinolines where only hydrogen gas and/or water are formed as the by-product(s). The mechanism is believed to involve the formation of a manganese(III) alkoxide complex which degrades into the aldehyde and a manganese(III) hydride species. The latter reacts with the alcohol to form hydrogen gas and thereby regenerates the alkoxide complex.

Methyl-phenyl derivatives, preparation method and use

The present invention relates to: a) methylbiphenyl derivatives of general formula: in which R1represents OH, C3-C7alkyl or C3-C7cycloalkyl, these compounds being in the form of individual isomers or mixtures thereof, b) their preparation by reaction: either of a hydroxylamine salt with an N-substituted o-(p-tolyl)benzaldimine, to give o-(p-tolyl)benzaldoxime or of an N-substituted 2-halobenzaldimine with a p-tolylmagnesium halide in the presence of an inorganic manganese derivative, to give the compounds of formula I in which R1represents C3-C7alkyl or C3-C7cycloalkyl c) their use for the preparation of o-(p-tolyl)-benzonitrile, which is an intermediate in the synthesis of medicinal products.