1157884-58-6

Basic information

• Product Name: ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate
• Synonyms: ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate
• CAS NO: 1157884-58-6
• Molecular Weight: 372.35
• Mol File: 1157884-58-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate(1157884-58-6)
• EPA Substance Registry System: ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate(1157884-58-6)

Safety Data

• Hazardous Substances Data: 1157884-58-6(Hazardous Substances Data)

Usage

General Description

The chemical compound ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate is a derivative of tetrahydrofuran with a benzoyloxy group attached to the 3-position and a methylbenzoate group attached to the 2-position. It also contains a fluorine atom at the 4-position and a ketone group at the 5-position. ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate has potential applications in pharmaceuticals, as it may exhibit biological activity due to its unique structure. The presence of the fluorine atom may also make it useful in organic synthesis as a chiral building block. Additionally, the benzoyloxy and methylbenzoate groups may contribute to its solubility and stability in various solvents.

Upstream product

• 98-88-4 benzoyl chloride 
• 492-30-8 2-C-methyl-D-ribono-1,4-lactone 
• 729596-46-7 3,5-di-O-benzoyl-2-C-methyl-D-ribono-γ-lactone 

Relevant articles and documents

Preparation method of fluorodesoxyribofuranose

The invention provides a preparation method of fluorodesoxyribofuranose. The structure of the fluorodesoxyribofuranose is represented by general formula 1 shown in the description; and the general formula 1, 1a:R = F, and R' = Me; and 1b:R = Me, and R' = F. The fluorodesoxyribofuranose prepared through the brand new preparation method can be used in researching of new medicines, or can be used in researches as a research model. The method adopts glyceraldehyde acetonide as a raw material and allows enantiomers in all intermediates to be effectively separated through a four-step reaction by adopting a rectification or distillation and re-crystallization technology, and a 2-posiion single optical isomer in the target product is directly constructed through an enol addition reaction, so the preparation of the target compound is smooth completed, and the method has the advantages of high yield, simple operation, and suitableness for promotion and application.

A neighboring group participation strategy: Facile synthesis of 3,5-di-O-benzoyl-2-C-methyl-d-arabino-γ-lactone

A simple and efficient approach for the synthesis of 3,5-di-O-benzoyl-2-C-methyl-d-arabino-γ-lactone through a neighboring group participation mechanism is reported. This compound could be a useful precursor for the synthesis of nucleoside antiviral agents.