1158956-66-1

Basic information

• Product Name: 5-hydroxy-1-(4-hydroxy-phenyl)-6-phenyl-hexan-3-one
• Synonyms: 5-hydroxy-1-(4-hydroxy-phenyl)-6-phenyl-hexan-3-one
• CAS NO: 1158956-66-1
• Molecular Weight: 284.355
• Mol File: 1158956-66-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-1-(4-hydroxy-phenyl)-6-phenyl-hexan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-1-(4-hydroxy-phenyl)-6-phenyl-hexan-3-one(1158956-66-1)
• EPA Substance Registry System: 5-hydroxy-1-(4-hydroxy-phenyl)-6-phenyl-hexan-3-one(1158956-66-1)

Safety Data

• Hazardous Substances Data: 1158956-66-1(Hazardous Substances Data)

Upstream product

• 522617-84-1 4-(4-trimethylsilyloxyphenyl)butan-2-one 
• 122-78-1 phenylacetaldehyde 

Relevant articles and documents

Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators

In order to explore the structural determinants for the TRPV1 and TRPA1 agonist properties of gingerols, aseries of nineteen analogues (1b-5) of racemic [6]-gingerol (1a) was synthesized and tested on TRPV1 and TRPA1 channels. The exploration of the structure-activity relationships, by modulating the three pharmacophoric regions of [6]-gingerol, led to the identification of some selective TRPV1 agonists/desensitizers of TRPV1 channels (3a, 3f, and 4) and of some full TRPA1 antagonists (2c, 2d, 3b, and 3d). 2011 Elsevier Ltd. All rights reserved.