1158984-54-3

Basic information

• Product Name: 4-chloro-2-hydrazinylPyrimidine
• Synonyms: 4-chloro-2-hydrazinylPyrimidine
• CAS NO: 1158984-54-3
• Molecular Weight: 0
• Mol File: 1158984-54-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-2-hydrazinylPyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2-hydrazinylPyrimidine(1158984-54-3)
• EPA Substance Registry System: 4-chloro-2-hydrazinylPyrimidine(1158984-54-3)

Safety Data

• Hazardous Substances Data: 1158984-54-3(Hazardous Substances Data)

Upstream product

• 3934-20-1 2,6-Dichloropyrimidine 

Relevant articles and documents

2, 6-DISUBSTITUTED PYRIDINES AND 2, 4-DISUBSTITUTED PYRIMIDINES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS

Disclosed are compounds of formula (I): wherein n represents 1 or 2; each R1 independently represents halo or trifluoromethyl; wherein halo represents fluoro, chloro or bromo; R2 represents hydrogen or C1-3alkyl; X represents N or CH; wherein -Z- represents a group selected from: (A), (B) or (C), wherein R3 represents trifluoromethyl or C1-3alkyl; and R4 represents hydrogen, trifluoromethyl or C1-3alkyl; with the proviso that where Z represents a thiophene group and X represents N, R2 cannot represent C1-3alkyl; and when X represents CH, -Z- can additionally represent a group selected from: (D) or (E) or salts thereof which activate soluble guanylate cyclase (sGC) pharmaceutical compositions containing them, their use is medicine, and processes for their preparation.