115934-15-1Relevant articles and documents
A FACILE PREPARATION OF 3-SUBSTITUTED 2-THIOXO-TETRAHYDROQUINAZOLIN-4-ONES BY THE REACTION OF ANTHRANILAMIDE WITH ISOTHIOCYANATES
Chan, Chao-Han,Shish, Fang-Jy,Liu, Kang-Chien,Chern, Ji-Wang
, p. 3193 - 3196 (2007/10/02)
3-Substituted 2-thioxo-tetrahydroquinazolin-4-ones (4a-d) can be synthesized in a convenient procedure directly by a treatment of anthranilamide with isothiocyanates at room temperature.However, anthranilamide was reacted with 4-isothiocyanato-1-benzylpiperidine (2e) leading to the formation of 2-thioureidobenzamide (3e) which was subsequently cyclized to 4e under a basic condition.