1159410-95-3Relevant articles and documents
An efficient one-pot copper-catalyzed approach to isoquinolin-1(2h)-one derivatives
Wang, Feng,Liu, Hongxia,Fu, Hua,Jiang, Yuyang,Zhao, Yufen
, p. 2469 - 2472 (2009)
A simple and efficient copper-catalyzed method for synthesis of 3,4-disubstituted isoquinolin-1(2H)-one derivatives via cascade reactions of substituted 2-halobenzamides with β-keto esters under mild conditions has been developed, and the method has econo
Heterogeneous copper-catalysed cascade reactions of 2-bromobenzamides with β-keto esters leading to isoquinolin-1(2H)-one derivatives
Zhao, Hong,Wu, Yichao,Wei, Tin,Cai, Mingzhong
, p. 634 - 638 (2015/01/09)
The heterogeneous copper-catalysed cascade reaction of 2-bromobenzamides with β-keto esters was achieved in dioxane at 80 °C in the presence of the MCM-41-immobilised bidentate nitrogen copper(I) complex [MCM-41-2N-CuI] with Cs2CO3 as base, affording a variety of isoquinolin-1(2H )-one derivatives in moderate to good yields. This heterogeneous copper catalyst can be recovered by a simple filtration and reused 10 times without significant loss of activity.