1159599-99-1

Basic information

• Product Name: 2-oxa-6-azaspiro[3,3]heptane oxalic acid salt
• Synonyms: 2-Oxa-6-azaspiro[3.3]heptane ethanedioate;2-Oxa-6-azaspiro[3.3]heptane oxalate;2-Oxa-6-azaspiro[3.3]heptane, ethanedioate (1:1);2-oxa-6-azaspiro[3.3]heptane, hemioxalate salt;2-oxa-6-azaspiro[3.3]heptane (Form: oxalate);2-oxa-6-azaspiro[3.3]heptan-6-ium carboxyformate;2-oxa-6-azaspiro[3,3]heptanes hemioxalate
• CAS NO: 1159599-99-1
• Molecular Formula: C₂H₂O₄*C₅H₉NO
• Molecular Weight: 189
• Mol File: 1159599-99-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 2-oxa-6-azaspiro[3,3]heptane oxalic acid salt(CAS DataBase Reference)
• NIST Chemistry Reference: 2-oxa-6-azaspiro[3,3]heptane oxalic acid salt(1159599-99-1)
• EPA Substance Registry System: 2-oxa-6-azaspiro[3,3]heptane oxalic acid salt(1159599-99-1)

Safety Data

• Hazardous Substances Data: 1159599-99-1(Hazardous Substances Data)

Usage

Description

2-Oxa-6-azaspiro[3,3]heptane oxalic acid salt is a chemical compound that serves as an intermediate in the synthesis of various pharmaceutical and chemical products. It is also utilized in the medical field for its potential therapeutic applications.

Uses

Used in Pharmaceutical and Chemical Synthesis:
2-Oxa-6-azaspiro[3,3]heptane oxalic acid salt is used as an intermediate in the pharmaceutical and chemical synthesis industry. It plays a crucial role in the development of new drugs and chemical products by acting as a building block or a key component in the synthesis process.
Used in Medicine:
In the medical field, 2-Oxa-6-azaspiro[3,3]heptane oxalic acid salt is used for its potential therapeutic applications. Its specific uses may vary depending on the particular medical application, but it is generally recognized for its ability to contribute to the development of new treatments and therapies.

InChI:InChI=1S/C5H9NO.C2H2O4/c1-5(2-6-1)3-7-4-5;3-1(4)2(5)6/h6H,1-4H2;(H,3,4)(H,5,6)

Upstream product

• 13573-28-9 6-(p-toluenesulfonyl)-2-oxa-6-azaspiro[3.3]heptane 
• 174-78-7 2-oxa-6-azaspiro[3.3]heptane 
• 144-62-7 oxalic acid 
• 1522-92-5 2,2-bis(bromomethyl)-3-bromo-propan-1-ol 
• 78-71-7 3,3-bis(chloromethyl)oxetane 
• 2402-83-7 3,3-bis(bromomethyl)oxetane 
• 46246-91-7 2-benzyl-6-oxa-2-azaspiro[3.3]-heptane 

Downstream Products

• 1240402-44-1 {3-[3-(4-Fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-isoxazol-5-yl}-(2-oxa-6-aza-spiro[3.3]hept-6-yl)-methanone 
• 1449279-91-7 N-((1S,2R)-2-hydroxy-3-oxo-1-phenyl-3-(2-oxa-6-azaspiro[3.3]heptan-6-yl)propyl)-benzamide 
• 1449279-92-8 tert-butyl (1S,2R)-2-hydroxy-3-oxo-1-phenyl-3-(2-oxa-6-azaspiro[3.3]heptan-6-yl)-propylcarbamate 
• 1449279-89-3 (4S,5R)-(3-benzoyl-2-(4-methoxyphenyl)-4-phenyloxazolidin-5-yl)(2-oxa-6-azaspiro[3.3]heptan-6-yl)methanone 
• 1449279-90-6 (4S,5R)-tert-butyl-2-(4-methoxyphenyl)-4-phenyl-5-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)oxazolidine-3-carboxylate 
• 1578244-77-5 N-(2-methoxy-4-(1-methyl-1H-pyrazol-4-yl)phenyl)-8-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrido[3,4-d]pyrimidin-2-amine 

Relevant articles and documents

SUBSTITUTED PHENYLOXAZOLIDINONES FOR ANTIMICROBIAL THERAPY

The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Design, synthesis and biological evaluation of novel azaspiro analogs of linezolid as antibacterial and antitubercular agents

The design, synthesis and antimicrobial evaluation of a novel series of azaspiro analogues of linezolid (1) have been described. Linezolid comprises of a morpholine ring which is known for its metabolism-related liabilities. Therefore, the key modificatio

Design, synthesis and biological evaluation of paclitaxel-mimics possessing only the oxetane D-ring and side chain structures

Two spiro paclitaxel-mimics consisting only of an oxetane D-ring and a C-13 side chain were designed and synthesized on the basis of analysis of structure-activity relationships (SAR) of paclitaxel. In vitro microtubule-stabilizing and antiproliferative assays indicated a moderate weaker activity of the mimics than paclitaxel, but which still represented the first example of simplified paclitaxel analogues with significant anti-tumor biological activity.