1159918-23-6Relevant articles and documents
A type III polyketide synthase from Rhizobium etli condenses malonyl CoAs to a heptaketide pyrone with unusually high catalytic efficiency
Jeya, Marimuthu,Kim, Tae-Su,Kumar Tiwari, Manish,Li, Jinglin,Zhao, Huimin,Lee, Jung-Kul
, p. 3103 - 3106 (2013/01/15)
A novel type III polyketide synthase (RePKS) from Rhizobium etli produced a heptaketide pyrone using acetyl-CoA and six molecules of malonyl-CoA. Its catalytic efficiency (kcat/Km = 5230 mM-1 min-1) for malonyl CoA was found to be the highest ever reported. Molecular dynamics studies revealed the unique features of RePKS. The Royal Society of Chemistry 2012.