1160457-28-2Relevant articles and documents
Rhodium-catalyzed intramolecular cyclization of naphthol- or phenol-linked 1,6-enynes through the cleavage and formation of sp2 C-O bonds
Sakiyama, Norifumi,Noguchi, Keiichi,Tanaka, Ken
, p. 5976 - 5980 (2012/07/03)
Put a ring on it: A cationic rhodium(I)/binap complex catalyzes the intramolecular cyclization reactions of naphthol- or phenol-linked 1,6-enynes to produce vinylnaphtho- or vinylbenzofurans and vinylnaphtho- or vinylbenzopyrans through the cleavage and f
Nazarov cyclization initiated by peracid oxidation: The total synthesis of (±)-rocaglamide
Malona, John A.,Cariou, Kevin,Frontier, Alison J.
supporting information; experimental part, p. 7560 - 7561 (2009/10/17)
(Chemical Equation Presented) The total syntheses of aglafolin, rocagloic acid, and rocaglamide using Nazarov cyclization are described. Generation of the necessary oxyallyl cation intermediate was accomplished via peracid oxidation of an allenol ether to generate an unusual oxycarbeniumion species that undergoes cyclization. The synthesis is efficient, hig hly diastereoselective, and strategically distinct from previous syntheses of rocaglamide.