1160848-98-5

Basic information

• Product Name: 5-[4-(2-chloroethoxy)phenyl]-6-methyl-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile
• Synonyms: 5-[4-(2-chloroethoxy)phenyl]-6-methyl-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile
• CAS NO: 1160848-98-5
• Molecular Weight: 416.91
• Mol File: 1160848-98-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[4-(2-chloroethoxy)phenyl]-6-methyl-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[4-(2-chloroethoxy)phenyl]-6-methyl-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile(1160848-98-5)
• EPA Substance Registry System: 5-[4-(2-chloroethoxy)phenyl]-6-methyl-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile(1160848-98-5)

Safety Data

• Hazardous Substances Data: 1160848-98-5(Hazardous Substances Data)

Upstream product

• 1160848-93-0 5-iodo-6-methyl-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile 
• 55162-34-0 1-bromo-4-(2-chloroethoxy)benzene 

Downstream Products

• 1160849-00-2 6-methyl-4-[(4-methyl-1H-indol-5-yl)amino]-5-{4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl}nicotinonitrile 

Relevant articles and documents

INDOLE-SUBSTITUTED 3-CYANOPYRIDINES AS KINASE INHIBITORS

Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein X is -O-, -N(R3)-, -S-, -S(O)- or -S(O)2-; R2 is a C1-4 alkyl group or -CF3; and R1, R3, R4 and p are as defined herein; wherein the compounds are useful as kinase inhibitors. Also disclosed are pharmaceutical compositions containing, and intermediate compounds and methods for making the compounds of formula (I) and their pharmaceutically acceptable salts; and methods of using the foregoing to treat inflammatory and autoimmune diseases such as asthma, colitis, multiple sclerosis, psoriasis, arthritis, rheumatoid arthritis, inflammatory bowel disease, and joint inflammation.