1162-78-3

Basic information

• Product Name: Phosphine, 2-naphthalenyldiphenyl-
• CAS NO: 1162-78-3
• Molecular Formula: C22H17P
• Molecular Weight: 312.351
• Mol File: 1162-78-3.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Phosphine, 2-naphthalenyldiphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine, 2-naphthalenyldiphenyl-(1162-78-3)
• EPA Substance Registry System: Phosphine, 2-naphthalenyldiphenyl-(1162-78-3)

Safety Data

• Hazardous Substances Data: 1162-78-3(Hazardous Substances Data)

Usage

General Description

Phosphine, 2-naphthalenyldiphenyl- is a chemical compound that is commonly used in the synthesis of organic phosphorus compounds. It is also known for its use as a ligand in coordination chemistry, where it forms stable complexes with transition metals such as copper and palladium. Phosphine, 2-naphthalenyldiphenyl- is a phosphine ligand with a naphthalene and diphenyl group attached to the phosphorus atom, providing a bulky and electron-rich environment for metal coordination. It is often used in catalytic reactions for the formation of carbon-carbon and carbon-heteroatom bonds, making it a valuable tool in organic synthesis. Overall, phosphine, 2-naphthalenyldiphenyl- plays a significant role in both academic research and industrial applications within the field of organophosphorus chemistry and metal-catalyzed reactions.

Upstream product

• 91-58-7 2-chloronaphthalene 
• 17154-34-6 (trimethylsilyl)diphenylphosphine 
• 3857-83-8 2-naphthyl triflate 
• 40841-62-1 (diphenylphosphino)(p-tolyl)methanone 
• 580-13-2 2-bromonaphthalene 
• 829-85-6 diphenylphosphane 
• 613-46-7 2-naphthalenecarbonitrile 
• 21333-65-3 Isopropyl-<2>naphthyl-carbonat 
• 135-19-3 β-naphthol 
• 1503-86-2 2-naphthyl pivalate 
• 4559-70-0 Diphenylphosphine oxide 
• 1101-41-3 Tetraphenyldiphosphin 
• 603-35-0 triphenylphosphine 
• 1079-66-9 chloro-diphenylphosphine 

Downstream Products

• 28402-08-6 (naphthalen-2-yl)diphenylphosphine oxide 
• 28225-52-7 8-(diphenylphosphino)quinoline 
• 5032-64-4 4-(diphenylphosphino)acetophenone 

Relevant articles and documents

Convenient and direct preparation of tertiary phosphines via nickel-catalysed cross-coupling

Nickel-catalysed cross-coupling of aryl sulfonates and aryl halides with chlorodiphenylphosphine and a reductant directly affords tertiary phosphines, which have application in a wide variety of asymmetric catalysis.

Palladium-Catalyzed C-P(III) Bond Formation by Coupling ArBr/ArOTf with Acylphosphines

Palladium-catalyzed C-P bond formation reaction of ArBr/ArOTf using acylphosphines as differential phosphination reagents is reported. The acylphosphines show practicable reactivity with ArBr and ArOTf as the phosphination reagents, though they are inert to the air and moisture. The reaction affords trivalent phosphines directly in good yields with a broad substrate scope and functional group tolerance. This reaction discloses the acylphosphines' capability as new phosphorus sources for the direct synthesis of trivalent phosphines.

Differentially Substituted Phosphines via Decarbonylation of Acylphosphines

A new route to phosphines was developed by a method that features a "pre-join and transform" process that proceeds via acylphosphine intermediates that may be readily prepared from carboxylic acids and disubstituted phosphines. The efficient decarbonylations of these acylphosphines using a nickel catalyst delivered the corresponding phosphines. This method shows that the carboxyl group can play a role similar to halides or triflates for introducing a substituted phosphorus atom on an aromatic ring.