116296-30-1 Usage
Description
(5-ACETYL-2-METHOXYPHENYL)ACETIC ACID, also known as ACEMETACIN, is a chemical compound with the molecular formula C10H10O4. It is a nonsteroidal anti-inflammatory drug (NSAID) that is used for the treatment of pain, inflammation, and fever. (5-ACETYL-2-METHOXYPHENYL)ACETIC ACID works by inhibiting the production of prostaglandins, which are chemical messengers responsible for promoting inflammation, pain, and fever in the body. The acetylation of the compound enhances its anti-inflammatory activity and makes it a more potent analgesic.
Uses
Used in Pharmaceutical Industry:
(5-ACETYL-2-METHOXYPHENYL)ACETIC ACID is used as a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of pain, inflammation, and fever. It is effective in managing conditions such as osteoarthritis, rheumatoid arthritis, and musculoskeletal pain due to its ability to inhibit the production of prostaglandins.
Used in Pain Management:
(5-ACETYL-2-METHOXYPHENYL)ACETIC ACID is used as an analgesic for the relief of mild to moderate pain. The acetylation of the compound enhances its anti-inflammatory activity, making it a more potent pain reliever.
Used in Inflammation Control:
(5-ACETYL-2-METHOXYPHENYL)ACETIC ACID is used as an anti-inflammatory agent to reduce inflammation in various conditions. Its ability to inhibit prostaglandin production helps in controlling inflammation and providing relief from associated symptoms.
Used in Fever Reduction:
(5-ACETYL-2-METHOXYPHENYL)ACETIC ACID is used as an antipyretic to reduce fever by lowering the body's temperature. It works by inhibiting the production of prostaglandins, which play a role in regulating body temperature.
Check Digit Verification of cas no
The CAS Registry Mumber 116296-30-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,2,9 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 116296-30:
(8*1)+(7*1)+(6*6)+(5*2)+(4*9)+(3*6)+(2*3)+(1*0)=121
121 % 10 = 1
So 116296-30-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O4/c1-7(12)8-3-4-10(15-2)9(5-8)6-11(13)14/h3-5H,6H2,1-2H3,(H,13,14)
116296-30-1Relevant articles and documents
Novel synthesis of benzofuran- and indol-2-yl-methanamine derivatives
Schlosser, Joachim,Johannes, Eugen,Zindler, Melanie,Lemmerhirt, Jan,Sommer, Benjamin,Schütt, Martin,Peifer, Christian
supporting information, p. 89 - 94 (2015/02/02)
We report on a novel synthesis towards benzofuran-2-yl-methanamine and indol-2-yl-methanamine derivatives by using ortho-methoxy and ortho-nitro substituted phenylacetic acids as starting material, respectively. For each compound series, a key intermediate bearing the oxazole-4-carboxylic acid methylester moiety was produced. Refluxing the ortho-methoxy series in HBr/HAc produced the desired benzofuran-2-yl-methanamines. Accordingly, for the synthesis of indoles the nitro-group was first reduced and refluxing these intermediates in HCl gave the corresponding indol-2-yl-methanamines. The method worked well with electron donating substituents. Limitations regarding electron withdrawing substituents are discussed. This straightforward synthetic procedure can be a useful approach to generate a variety of substituted benzofuran-2-yl-methanamine and indol-2-yl-methanamine compounds by starting from readily available phenylacetic acid derivatives.
Gamma-ketoacid dipeptides as inhibitors of caspase-3
-
, (2008/06/13)
This invention encompasses the novel compounds of Formula I, which are useful in the treatment of caspase-3 mediated diseases. The invention also encompasses certain pharmaceutical compositions comprising compounds of Formula I as well as methods for treatment of caspase-3 mediated diseases.
