116308-38-4

Basic information

• Product Name: 4-Pyridinecarbonitrile,2-formyl-(9CI)
• Synonyms: 4-Pyridinecarbonitrile,2-formyl-(9CI);4-Cyanopyridine-2-carboxaldehyde;2-forMyl-4-pyridinecarbonitrile;2-forMylisonicotinonitrile;2-Formylpyridine-4-carbonitrile;4-Cyano-2-pyridinecarboxaldehyde
• CAS NO: 116308-38-4
• Molecular Formula: C₇H₄N₂O
• Molecular Weight: 132.122
• Product Categories: PYRIDINE
• Mol File: 116308-38-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 201.0±20.0℃ (760 Torr)
• Flash Point: 75.4±21.8℃
• Appearance: /
• Density: 1.24±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.45±0.10(Predicted)
• CAS DataBase Reference: 4-Pyridinecarbonitrile,2-formyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarbonitrile,2-formyl-(9CI)(116308-38-4)
• EPA Substance Registry System: 4-Pyridinecarbonitrile,2-formyl-(9CI)(116308-38-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22-43
• Safety Statements: 36/37
• Hazardous Substances Data: 116308-38-4(Hazardous Substances Data)

Usage

General Description

4-Pyridinecarbonitrile,2-formyl-(9CI) is a chemical compound with the molecular formula C7H4N2O. It is also known by its IUPAC name 2-formylpyridine-4-carbonitrile. 4-Pyridinecarbonitrile,2-formyl-(9CI) is a derivative of pyridine, a six-membered heterocyclic ring containing five carbon atoms and one nitrogen atom. It is commonly used in the production of pharmaceuticals and agrochemicals. Its properties and reactivity make it a valuable building block for the synthesis of various organic compounds. 4-Pyridinecarbonitrile,2-formyl-(9CI) is an important intermediate in the pharmaceutical and chemical industries, and its unique chemical structure makes it useful in a wide range of applications.

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 98549-84-9 4-Cyano-2-picoline-N-oxide 
• 2214-53-1 2-methyl-4-cyanopyridine 
• 931-19-1 2-methylpyridine N-oxide 
• 51454-63-8 4-cyano-2-hydroxymethylpyridine 
• 30342-68-8 N-Ethoxy-2-picolinium iodide 
• 51454-62-7 2-acetoxymethyl-isonicotinonitrile 

Downstream Products

• 108337-75-3 2-(N-Benzyl-N-methylamino)ethyl Methyl 4-(4-Cyano-2-pyridyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 
• 185220-30-8 2-(1'-hydroxyethyl)-4-acetylpyridine 
• 106474-82-2 4-cyano-2-(2-hydroxy)-ethylpyridine 
• 236397-68-5 2-[4-(2,6-dichloro-4-trifluoromethyl-phenyl)-5-imino-4,5-dihydro-[1,3,4]thiadiazol-2-yl]-isonicotinonitrile 
• 116308-51-1 2-<4-(4-benzhydryl-1-piperazinyl)phenyl>ethyl methyl 4-(4-cyano-2-pyridyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylate 
• 116308-47-5 2-(p-Dibenzylaminophenyl)ethyl methyl 2,6-dimethyl-4-(4-cyano-pyridin-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate 
• 116308-66-8 2-(4-dimethylaminophenyl)ethyl methyl 4-(4-cyano-2-pyridyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 
• 134364-85-5 2-<4-(4-benzhydryl-1-piperazinyl)phenyl>ethyl 2-(4-cyano-2-pyridylmethylidene)acetoacetate 
• 116308-81-7 2-[N-methyl-N-(2-diphenylaminoethyl)amino]ethyl methyl 2,6-di-methyl-4-(4-cyano-2-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylate 
• 877843-00-0 2-[3-oxo-3H-isobenzofuran-(1E,Z)-ylidenemethyl]-isonicotinonitrile 

Relevant articles and documents

Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues

Fifty novel prodrugs and aza-analogues of 3,5-bis(4-amidinophenyl)isoxazole and its derivatives were prepared. Eighteen of the 24 aza-analogues exhibited IC50 values below 25 nM against Trypanosoma brucei rhodesiense or Plasmodium falciparum. S

Alpha-substituted pyrimidine-thioalkyl and alkylether compounds as inhibitors of viral reverse transcriptase

The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula (I) and pyrimidine-thioalkyl and alkylethers of Formula (IA), namely the compounds of Formula (I) where R 4 is selected from the group consisitng of --H or --NR 15 R 16 where R 15 is --H and R 16 is --H, C 1 -C 6 alkyl, NH 2 or R 15 and R 16 taken together with the --N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and R 6 is selected from the group consisting of --H, or halo (preferably --Cl); with the overall proviso that R 4 and R 6 are not both --H. The compounds of Formula (IA) are useful in the treatment of individuals who are HIV positive being inhibitors of viral reverse transcriptase. STR1