116498-58-9

Basic information

• Product Name: 5,5'-Dimethoxylariciresil
• Synonyms: 5,5'-Dimethoxylariciresil;5,5'-DiMethoxylariciresinol
• CAS NO: 116498-58-9
• Molecular Formula: C₂₂H₂₈O₈
• Molecular Weight: 420.45292
• Mol File: 116498-58-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 609.8±55.0 °C(Predicted)
• Appearance: /
• Density: 1.260±0.06 g/cm3(Predicted)
• PKA: 9.92±0.40(Predicted)
• CAS DataBase Reference: 5,5'-Dimethoxylariciresil(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5'-Dimethoxylariciresil(116498-58-9)
• EPA Substance Registry System: 5,5'-Dimethoxylariciresil(116498-58-9)

Safety Data

• Hazardous Substances Data: 116498-58-9(Hazardous Substances Data)

Usage

General Description

5,5'-Dimethoxylariciresinol (5,5'-DML) is a lignan compound found in various plant sources, including flaxseed and sesame seeds. It is known for its antioxidant and anti-inflammatory properties, and has been studied for its potential health benefits, such as reducing the risk of certain chronic diseases. 5,5'-DML has also shown promise in inhibiting the growth of cancer cells and promoting cardiovascular health. Additionally, it has been investigated for its potential use in skincare and cosmetics due to its anti-aging and skin-protective effects. Overall, 5,5'-Dimethoxylariciresinol is a natural compound with potential therapeutic and commercial applications.

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Relevant articles and documents

Lignan and neolignan glycosides from stems of Alangium premnifolium

From a methanol extract of stems of Alangium premnifolium, eight lignan derivatives were isolated. Structural elucidation by a spectroscopic method revealed that four of them were new lignan or neolignan glycosides.

Lignan Glycosides from the Twigs of Chaenomeles sinensis and Their Biological Activities

Phytochemical investigation of the twigs of Chaenomeles sinensis led to the isolation and identification of six new lignan glycosides, chaenomiside A-F (1-6), along with five known ones (7-11). Their chemical structures were determined by spectroscopic methods, including NMR, MS, ECD, and GC/MS analyses. All the isolated compounds (1-11) were tested for their inhibitory effects on nitric oxide (NO) production in lipopolysaccharide-activated murine microglial cells and the secretion of nerve growth factor (NGF) in a C6 rat glioma cell line. Compound 6 significantly reduced NO levels in the murine microglia BV2 cells with an IC50 value of 21.3 μM, and compounds 1, 3, and 6 were potent stimulants of NGF release with stimulation levels of 151.74 ± 6.77%, 144.31 ± 7.49%, and 167.61 ± 18.5%, respectively.

Two new lignan xylosides from the barks of Prunus ssiori and Prunus padus

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