116529-35-2

Basic information

• Product Name: 2,4-DICHLOROBENZYL IODIDE
• Synonyms: 2,4-DICHLOROPHENYLMETHYL IODIDE;2,4-DICHLOROBENZYL IODIDE;1,3-Dichloro-4-(iodomethyl)benzene;Benzene, 2,4-dichloro-1-(iodomethyl)-
• CAS NO: 116529-35-2
• Molecular Formula: C₇H₅Cl₂I
• Molecular Weight: 286.93
• Mol File: 116529-35-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 284.7 °C at 760 mmHg
• Flash Point: 126 °C
• Appearance: /
• Density: 1.932 g/cm³
• Vapor Pressure: 0.00504mmHg at 25°C
• Refractive Index: 1.646
• CAS DataBase Reference: 2,4-DICHLOROBENZYL IODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DICHLOROBENZYL IODIDE(116529-35-2)
• EPA Substance Registry System: 2,4-DICHLOROBENZYL IODIDE(116529-35-2)

Safety Data

• Hazardous Substances Data: 116529-35-2(Hazardous Substances Data)

Usage

General Description

2,4-Dichlorobenzyl iodide is a chemical compound that is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. It is a member of the benzyl halide family and contains two chlorine atoms attached to a benzene ring, with an iodine atom replacing a hydrogen atom. 2,4-Dichlorobenzyl iodide is a versatile building block in organic synthesis and is commonly used in the pharmaceutical industry to create various medications. It is also used in the production of insecticides and herbicides, as well as in the synthesis of other organic compounds. 2,4-DICHLOROBENZYL IODIDE is a valuable tool for chemists and researchers in the development of new drugs and agrochemicals.

InChI:InChI=1/C7H5Cl2I/c8-6-2-1-5(4-10)7(9)3-6/h1-3H,4H2

Upstream product

• 1777-82-8 (2,4-dichlorophenyl)methanol 
• 60211-56-5 2,4-dichlorobenzyl fluoride 
• 94-99-5 2,4-Dichlorobenzyl chloride 
• 1058649-24-3 2,4-dichloro-1-[(ethoxymethoxy)methyl]benzene 
• 877468-98-9 2,4-dichloro-1-(methoxymethoxy)methyl benzene 

Downstream Products

• 206066-36-6 3-(2,4-dichlorobenzyl)-5-methoxycarbonyl-2-methylindole 
• 206066-32-2 3-(2,4-dichlorobenzyl)-5-methoxycarbonylindole 
• 521098-39-5 (R)-3-(2,4-dichlorophenyl)-2-methylpropanoic acid 
• 13616-24-5 1,6-bis-(2,4-dichloro-benzylsulfanyl)-[1,4]dithiino[2,3-d;5,6-d']dipyridazine 
• 109257-66-1 1-(2,4-dichloro-benzyl)-tetrahydro-thiophenium; iodide 

Relevant articles and documents

Selective iodination of benzylic alcohols with KI/H2SO4 supported on natural kaolinitic clay under microwave irradiation

Benzylic alcohols are selectively converted into their corresponding iodides using KI/H2SO4 supported on natural kaolinitic clay and microwaves.

Ionic liquid-induced conversion of methoxymethyl-protected alcohols into nitriles and iodides using [Hmim][NO3]

This Letter reports a one-pot efficient conversion of methoxymethyl-ethers into their corresponding nitriles and iodides using the ionic liquid, 1-methyl-3H-imidazolium nitrate ([Hmim][NO3]) under microwave irradiation. A variety of products were prepared in high yields using this method.

Microwave-promoted, one-pot conversion of alkoxymethylated protected alcohols into their corresponding nitriles, bromides, and iodides using [bmim][InCl4] as a green catalyst

The Lewis acid room temperature ionic liquid, [bmim][InCl4], was found to be an efficient and green catalyst for the highly chemoselective and one-pot conversion of MOM- or EOM-ethers into their corresponding nitriles, bromides, and iodides under microwave irradiation. The procedures are simple, rapid, and high yielding. The catalyst exhibited a remarkable reactivity and is reusable.