116539-95-8Relevant articles and documents
Synthese de 2,3,4,4a,9,9a-Hexahydro-11-indenopyrazines, Analogues Rigides de 3-Methyl-2-phenylpiperazines et Antidepresseurs Potentiels
Chahboun, S.,Gelbcke, M.,Vliedt, G. Van De,Smith, D. F.
, p. 287 - 296 (2007/10/03)
The synthesis of various diastereoisomeric (+/-) trans-(VIII) and cis-2,3,4,4a,9,9a-hexahydro-1H-indenopyrazines (IX) is described, using as key step for piperazine ring formation an alkoxyphosphonium salt.Compound VIIIa was prepared as a potential serotonin reuptake inhibitor.