116548-02-8 Usage
Description
1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester is a chemical compound that belongs to the class of pyridinecarboxylic acid esters. It is characterized by the presence of a trifluoromethyl group at the 6-position of the pyridine ring, which imparts unique chemical and biological properties to the molecule. 1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester is known for its potential use in the synthesis of trifluoromethylated pyridine derivatives, which have shown promising pharmacological activities.
Uses
Used in Pharmaceutical Industry:
1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester is used as a key intermediate in the synthesis of trifluoromethylated pyridine derivatives. These derivatives have been identified as potential antihypertensive agents, making this compound an important reagent in the development of new drugs for the treatment of hypertension.
In the pharmaceutical industry, the trifluoromethyl group is known to enhance the lipophilicity and metabolic stability of drug molecules, which can lead to improved bioavailability and efficacy. The introduction of this group in pyridine derivatives has been shown to modulate their binding affinity to various biological targets, such as enzymes and receptors, involved in the regulation of blood pressure.
Furthermore, the ethyl ester functionality in 1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester can be easily hydrolyzed to the corresponding carboxylic acid, which can then be further derivatized to generate a diverse range of trifluoromethylated pyridine analogs with tailored pharmacological properties.
Overall, 1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester plays a crucial role in the discovery and development of novel antihypertensive agents, contributing to the advancement of therapeutic options for the management of hypertension and its associated complications.
Check Digit Verification of cas no
The CAS Registry Mumber 116548-02-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,5,4 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 116548-02:
(8*1)+(7*1)+(6*6)+(5*5)+(4*4)+(3*8)+(2*0)+(1*2)=118
118 % 10 = 8
So 116548-02-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H8F3NO3/c1-2-16-8(15)5-3-4-6(9(10,11)12)13-7(5)14/h3-4H,2H2,1H3,(H,13,14)
