116652-76-7Relevant articles and documents
The total synthesis of scytophycin C. Part 1: Stereocontrolled synthesis of the C1-C32 protected seco acid
Paterson, Ian,Yeung, Kap-Sun,Watson, Christine,Ward, Richard A.,Wallace, Paul A.
, p. 11935 - 11954 (1998)
A stereocontrolled synthesis of the C1-C32 seco acid derivative 9 for scytophycin C (1) was completed in 14 steps (18.2% yield, 85% ds) from aldehyde (S)-18. Key steps include: (i) the asymmetric crotylboration of (S)- 18 to give hom
Studies towards the synthesis of tedanolide C. Construction of the C13-epi C1-C15 fragment
Zambrana, Joana,Romea, Pedro,Urpí, Fèlix
, p. 5219 - 5223 (2016/07/06)
The preparation of an advanced intermediate on route towards the synthesis of tedanolide C is reported here. It is based on the coupling of two fragments of similar size and complexity, which in turn are prepared by highly stereoselective substrate-contro
Stereocontrolled total synthesis of (+)-concanamycin F: The strategic use of boron-mediated aldol reactions of chiral ketones
Paterson, Ian,Steadman Neé Doughty, Victoria A.,McLeod, Malcolm D.,Trieselmann, Thomas
supporting information; experimental part, p. 10119 - 10128 (2012/01/14)
A highly stereocontrolled total synthesis of the 18-membered macrolide (+)-concanamycin F, a potent inhibitor of vacuolar ATPases, is described that proceeds in 5.8% yield over 26 steps. The three key fragments, C1-C13 vinyl iodide, C14-C22 vinyl stannane