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116700-73-3

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116700-73-3 Usage

Physical state

Colorless, flammable liquid

Odor

Faint

Use

Reagent in organic synthesis, protective agent for hydroxyl groups in organic compounds

Applications

Modification of natural products, synthesis of pharmaceuticals, agrochemicals, and functional materials

Properties

Ability to form stable silicon-oxygen bonds, useful in chemical transformations and as a protecting group in the synthesis of complex organic molecules

Importance

Versatile and valuable reagent in organic chemistry

Check Digit Verification of cas no

The CAS Registry Mumber 116700-73-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,7,0 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 116700-73:
(8*1)+(7*1)+(6*6)+(5*7)+(4*0)+(3*0)+(2*7)+(1*3)=103
103 % 10 = 3
So 116700-73-3 is a valid CAS Registry Number.

116700-73-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[[tert-butyl(dimethyl)silyl]oxymethyl]prop-2-en-1-ol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:116700-73-3 SDS

116700-73-3Downstream Products

116700-73-3Relevant articles and documents

Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in staphylococcus aureus

Bouton, Jakob,Van Hecke, Kristof,Rasooly, Reuven,Van Calenbergh, Serge

, p. 2822 - 2828 (2018)

Interfering with bacterial cell-to-cell communication is a promising strategy to combat antimicrobial resistance. The natural product hamamelitannin and several of its analogues have been identified as quorum sensing inhibitors. In this paper the synthesi

Synthesis of novel 6,11-o-bridged bicyclic ketolides via a palladium-catalyzed bis-allylation

Wang, Guoqiang,Niu, Deqiang,Qiu, Yao-Ling,Phan, Ly Tam,Chen, Zhigang,Polemeropoulos, Alexander,Or, Yat Sun

, p. 4455 - 4458 (2004)

(Chemical equation presented) A bridging chemistry process was developed to form an ether bridge between 6-O and 11-O of erythromycin A via a tandem or stepwise palladium-catalyzed bis-π-allylation. By applying this bridging process, new 6,11-O-bridged bicyclic ketolides (BBKs) were synthesized. These BBKs showed good antibacterial activities against the macrolide-susceptible strains as well as mef-resistant strains and served as a good core for further modifications to study the structure-activity relationship (SAR) and to overcome bacterial resistance.

All-Carbon [3+3] Oxidative Annulations of 1,3-Enynes by Rhodium(III)-Catalyzed C-H Functionalization and 1,4-Migration

Burns, David J.,Best, Daniel,Wieczysty, Martin D.,Lam, Hon Wai

, p. 9958 - 9962 (2015)

1,3-Enynes containing allylic hydrogens cis to the alkyne function as three-carbon components in rhodium(III)-catalyzed, all-carbon [3+3] oxidative annulations to produce spirodialins. The proposed mechanism of these reactions involves the alkenyl-to-ally

Enantioselective hydroesterificative cyclization of 1,6-enynes to chiral γ-lactams bearing a quaternary carbon stereocenter

Dong, Kaiwu,Li, Huimin,Ren, Xinyi,Shen, Chaoren,Tang, Lin,Wang, Peng

supporting information, p. 3561 - 3566 (2021/05/29)

A palladium-catalyzed asymmetric hydroesterification-cyclization of 1,6-enynes with CO and alcohol was developed to efficiently prepare a variety of enantioenriched γ-lactams bearing a chiral quaternary carbon center and a carboxylic ester group. The approach featured good to high chemo-, region-, and enantioselectivities, high atom economy, and mild reaction conditions as well as broad substrate scope. The correlation between the multiple selectivities of such process and the N-substitutes of the amide linker in the 1,6-enyne substrate has been depicted by the crystallographic evidence and control experiments.

NEW SUBSTITUTED AZAINDOLINE DERIVATIVES AS NIK INHIBITORS

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Page/Page column 159; 160, (2019/01/21)

The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-κB-inducing kinase (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.

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