1169199-21-6

Basic information

• Product Name: Cbz-Ala-ψ[CH2SO2]-F
• Synonyms: Cbz-Ala-ψ[CH2SO2]-F
• CAS NO: 1169199-21-6
• Molecular Weight: 275.301
• Mol File: 1169199-21-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cbz-Ala-ψ[CH2SO2]-F(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-Ala-ψ[CH2SO2]-F(1169199-21-6)
• EPA Substance Registry System: Cbz-Ala-ψ[CH2SO2]-F(1169199-21-6)

Safety Data

• Hazardous Substances Data: 1169199-21-6(Hazardous Substances Data)

Upstream product

• 1300689-92-2 C₁₁H₁₄NO₅S^(1-)*Na⁽¹⁺⁾ 
• 1140948-95-3 Cbz-Ala-ψ[CH2SO2]-Cl 
• 501-53-1 benzyl chloroformate 
• 83197-70-0 (S)-2-(benzyloxycarbonylamino)propyl methanesulfonate 
• 25172-67-2 Z-Ala-O-COO-isoBu 
• 6429-44-3 (S)-(-)-N-(benzyloxycarbonyl)alaninol 
• 1142-20-7 N-Cbz-Ala 
• 1300858-65-4 C₁₁H₁₅NO₅S 
• 1140948-93-1 (S)-2-benzyloxycarbonylaminopropyl thiolacetate 

Relevant articles and documents

SuFExable Isocyanides for Ugi Reaction: Synthesis of Sulfonyl Fluoro Peptides

Herein, the sulfonyl fluoro isocyanides were first developed as a new type of SuFExable synthon, and they are used as building blocks in the Ugi reaction (U-4CR). The Ugi reaction was established and the substrate scope was investigated, and various sulfonyl fluoro α-amino amides and peptides could be reached in a one-step synthesis. Therefore, this protocol opens a new vision for SuFExable building blocks and click chemistry, and it also provides a distinct approach to sulfonyl fluoro peptides.

Synthesis of β-aminoethanesulfonyl fluorides or 2-substituted taurine sulfonyl fluorides as potential protease inhibitors

Substituted taurine sulfonyl fluorides derived from taurine or protected amino acids are conveniently synthesized from β-aminoethanesulfonyl chlorides using KF/18-crown-6 or from β-aminoethanesulfonates using DAST.