116998-18-6Relevant articles and documents
Cyclocondensation of Alkylhydrazines and β-Substituted Acetylenic Esters: Synthesis of 3-Hydroxypyrazoles
Hamper, Bruce C.,Kurtzweil, Mitchell L.,Beck, James P.
, p. 5680 - 5686 (2007/10/02)
Addition of monosubstituted alkylhydrazines to acetylenic esters with either electron-withdrawing or sterically bulky β-substituents afforded 1-alkyl-3-hydroxy-5-substituted-pyrazoles 1 as the major regioisomeric product.By comparison, the classical cyclo