117020-71-0

Basic information

• Product Name: 3-epi-17βH-periplogenin
• Synonyms: 3-epi-17βH-periplogenin
• CAS NO: 117020-71-0
• Molecular Weight: 390.52
• Mol File: 117020-71-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-epi-17βH-periplogenin(CAS DataBase Reference)
• NIST Chemistry Reference: 3-epi-17βH-periplogenin(117020-71-0)
• EPA Substance Registry System: 3-epi-17βH-periplogenin(117020-71-0)

Safety Data

• Hazardous Substances Data: 117020-71-0(Hazardous Substances Data)

Upstream product

• 57-50-1 Sucrose 
• 143-62-4 (+)-digitoxigenin 
• 221380-14-9 neridiginoside 
• 143-62-4 digitoxigenin 

Downstream Products

• 18531-44-7 periplogenin glucoside 
• 6246-62-4 14-hydroxy-14β-carda-3,5,20(22)-trienolide 

Relevant articles and documents

Biotransformation of digitoxigenin by cultured Strophanthus hybrid cells

Hybrid cells between Strophanthus gratus and S. amboensis were obtained by electrofusion and confirmed to be hybrids through isozyme and RFLP analyses. Because a new and hybrid compound, 17βH-periplogenin β-D- glucoside, was isolated as a biotransformation product of digitoxigenin by the hybrid cells, isomerization of 17β-lactone ring on S. gratus and glucosylation on S. amboensis were demonstrated simultaneously as the biotransformation abilities in the hybrid cells. Moreover, the productivity of the hybrid compound was increased by raising the sucrose concentration.

Biotransformation of digitoxigenin by cultured ginseng cells

Nine compounds, including a new compound (digitoxigenin β-D-glucoside malonyl ester), were isolated as biotransformation products of digitoxigenin by cell suspension cultures of Panax ginseng (Pg-3 cell line). At the same time, two known products were identified by TLC and HPLC.

BIOTRANSFORMATION OF DIGITOXIGENIN BY CELL SUSPENSION CULTURES OF STROPHANTHUS DIVARICATUS

Eight compounds, including a new compound (3-epi-17βH-gitoxigenin) were isolated as biotransformation products of digitoxigenin by cell suspension cultures of Strophanthus divaricatus.At the same time, three products were identified by TLC and HPLC. 16β-Hydroxylation and isomerization of the 17β-butenolide ring of digitoxigenin molecule were demonstrated using this cell suspension culture. Key Word Index - Strophanthus divaricatus; Apocynaceae; biotransformation; 16β-hydroxylation; isomerization of 17β-butenolide ring; cardenolides; digitoxigenin; 17βH-gitoxigenin; 3-epi-17βH-gitoxigenin.